South Dakota State vs Iowa State Prediction, Picks, Odds | NCAA Tournament First Round Bets

South Dakota State vs Iowa State Prediction, Picks, Odds | NCAA Tournament First Round Bets

The First Round of NCAA Men's Basketball Tournament kicks off on Thursday, March 21 -- and the 12th matchup on the slate set to tip off is South Dakota State vs Iowa State, which is scheduled for 7:35 p.m. ET on truTV.

The Cyclones have climbed to 16.5-point favorites on the spread for Thursday's contest after originally opening at -14.5; with the game total stationed around over/under 135 at most sportsbooks.

Here's everything you need to know about South Dakota State vs Iowa State -- our expert prediction and betting picks for this First Round NCAA Tournament matchup.

South Dakota State vs Iowa State Odds

SDKST @ IAST Odds

South Dakota State vs Iowa State Prediction

Iowa State turned plenty of heads in the Big 12 championship by routing top-seed Houston, 69-41 as 5.5-point underdogs.

The Cyclones are the 2nd seed in the East region, but don't get much of a home-court advantage in Omaha as they face Summit League champion South Dakota State.

Iowa State owned the best defense efficiency ranking in the country, while holding Kansas State, Baylor, and Houston to 62 points or fewer in the Big 12 tournament.

The Jackrabbits will fire away as they rank 50th in the country in 3-point shooting at 36.2%, as South Dakota State is listed in its highest underdog spot of the season.

The expectations are high for Iowa State off the Big 12 tournament title as this is only the second time the Cyclones are a favorite in the Big Dance since 2021.

Pick: South Dakota State +16.5 (-110)

South Dakota State vs Iowa State Game Time & TV Channel

Date: Thursday, March 21
Matchup: Summit vs Big 12
Venue: CHI Health Center Omaha
Location: Omaha, Nebraska
Time-TV: truTV, 7:35 p.m. ET

South Dakota State vs Iowa State Betting Stats

2) Iowa State Cyclones
(Big 12, Automatic)

  • Futures: +1900
  • Region: +550
  • SU: 27-7
  • ATS: 22-10-2
  • O/U: 16-18
  • PPG: 75.7
  • OPPG: 62.1

15) South Dakota State Jackrabbits
(Summit, Automatic)

  • Futures: +40000
  • Region: +15000
  • SU: 22-12
  • ATS: 17-14
  • O/U: 15-15-1
  • PPG: 77.3
  • OPPG: 71.9

March Madness Betting Resources

March Madness First Round Odds

The NCAA Men's Tournament First Round will take place on Thursday March 21, 2024 and Friday March 22, 2024.

Check out the Teams, Odds, Betting Stats and much more on each of the four regions below: