College Football Odds Week 10: LSU vs Alabama Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline
Alabama vs
LSU
-3.5 (-100)
+3.5 (-122)
o61.5 (-105)
u61.5 (-115)
-164
+136

Week 10 of the college football season continues with a clash between SEC royalty as LSU visits Alabama. The betting odds favor the Crimson Tide by a field goal seeking their seventh straight victory since falling to Texas in Week 2. Coverage begins from Bryant-Denny Stadium in Tuscaloosa on Saturday, November 4 at 7:45 p.m. ET on CBS.

Here's everything you need to know about the college football odds for Week 10 LSU vs. Alabama: the opening lines, spreads, betting trends and more. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

No. 13 LSU vs No. 8 Alabama Odds

Alabama QB Jalen Milroe gets a stern test this week against LSU. (Getty)
  • Opening point spread: Alabama -3.5
  • Opening moneyline: Alabama -182/LSU +148
  • Opening total: Over/Under 60 points scored
  • Time: 7:45 p.m. ET Saturday (CBS)

UPDATE 7 P.M. ET SATURDAY: At BetMGM, Alabama opened -4.5 and tumbled to -2.5 (-115) by Monday afternoon. The Crimson Tide quickly rebounded to -3 (-105), then went to -3 (-115) Tuesday, and the line hasn't moved since.

"We're definitely rooting for LSU to win outright. Alabama is a big public spot," BetMGM senior trader Cameron Drucker said.

UPDATE 6:30 P.M. ET THURSDAY: On Sunday afternoon, the Crimson Tide opened -3.5 in The SuperBook's college football odds Week 10 market. Alabama dipped to -3 Monday, and there's been no movement since.

"More tickets and money on Alabama, straight bets and parlays," Degnon said. "That doesn't surprise me with Alabama, especially laying a short number at home. We did take some respected play on LSU +3.5, and that bumped us to 3."

The total opened at 60, went to 60.5 Tuesday and 61 Wednesday.

UPDATE 3 P.M. ET MONDAY: Alabama (7-1 SU/5-3 ATS) hopes to stay in line as the top one-loss team in the College Football Playoff odds chase. The Crimson Tide had a Week 9 bye, after beating Tennessee 34-20 as 8.5-point home favorites in Week 8.

LSU (6-2 SU/5-3 ATS) is pretty much already out of the CFP chase, though it can certainly play the role of big spoiler. Like 'Bama, the Tigers also had a Week 9 bye. In Week 8, LSU blasted Army 62-0 laying 32.5 points at home.

TwinSpires moved Alabama from -3.5 to -3. The Crimson Tide are seeing 72% of early spread bets, while 59% of early spread cash is on the Tigers.

"It's Pros vs. Joes. The sharp side is LSU +3.5," Lucas said.

The total is stable at 60, with 65% of bets/73% of cash on the Over.

Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 10 Report containing spreads, lines, and trends for every Top 25 matchup.