College Football Odds Week 10: Virginia Tech vs Louisville Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

1 minute read

Louisville continues to play well as it looks to stay hot against Virginia Tech in Week 10 of college football. Betting odds see the Cardinals as 9.5-point home favorites against the Hokies. Coverage begins from Louisville on Saturday, November 4 at 3:30 p.m. ET on ACC Network.

Here's everything you need to know about the college football odds for Week 10 Virginia Tech vs Louisville: the opening lines, spreads, betting trends and more. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

Virginia Tech vs No. 15 Louisville Odds

• Opening point spread: Louisville -10.5.
• Opening moneyline: Louisville -420/Virginia Tech +320
• Opening total: Over/Under 48.5 points scored
• Time: 3:30 p.m. ET Saturday (ACC Network)

UPDATE 1:30 P.M. ET FRIDAY: The Cardinals opened -10.5 Sunday night at BetMGM, fell to -9.5 Monday morning and have been stable ever since. Tickets and money are running 4/1 on Louisville.

The total opened at 48.5, went to 48 Wednesday and back to 48.5 Thursday. The Under is taking 58% of bets and a lopsided 90% of money so far.

UPDATE 3 P.M. ET MONDAY: Louisville (7-1 SU/4-3-1 ATS) bounced back from its Week 7 loss at Pittsburgh. The Cardinals, fresh off a bye, dumped No. 20 Duke 23-0 giving 4.5 points at home.

Virginia Tech (4-4 SU/5-3 ATS) rolled past Syracuse 38-10 as 2.5-point home chalk. The Hokies have covered in four straight games.

Louisville is already down a point at Caesars, with moves early today to -10/-9.5. The total is up a tick to 49.

Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 10 Report containing spreads, lines, and trends for every Top 25 matchup.

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson