College Football Odds Week 11: Virginia vs Louisville Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline

The first ACC game of Week 11 of college football takes place in Louisville as the Cardinals host Virginia. Betting odds see the Cardinals as 20.5-point home favorites against the Cavaliers. Coverage begins from Louisville on Thursday, November 9 at 7:30 p.m. ET on ESPN.

Here's everything you need to know about the college football odds for Week 11 Virginia vs Louisville: the opening lines, spreads, betting trends, best sportsbook bonus, and more. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

Virginia vs No. 11 Louisville Odds

Louisville seeks another home win against Virginia on Thursday. (Getty)
  • Opening point spread: Louisville -20
  • Opening moneyline: Louisville -1400/Virginia +800
  • Opening total: Over/Under 51.5 points scored
  • Time: 7:30 p.m. ET Thursday (ESPN)

UPDATE 5:30 P.M. ET THURSDAY: The Cardinals opened as 20-point favorites and crept up to -20.5 Wednesday night at PointsBet, a Fanatics Experience. It's all Louisville on the spread, with ticket count 3/1 and money almost 8/1.

The total opened at 50.5 and quickly moved to 51.5 Sunday night. The number returned to 50.5 Monday afternoon and stuck there until dipping 50 this afternoon. Contrary to the move down, ticket count is 2.5/1 and money almost 8/1 on the Over.

UPDATE 3 P.M. ET MONDAY: Louisville (8-1 SU/5-3-1 ATS) had zero issues with Virginia Tech in Week 10. The Cardinals rolled to a 34-3 victory as 9-point home favorites.

Virginia has been awful on the field at 2-7 SU, but pretty good at the betting window at 6-3 ATS. In Week 10, however, the Cavaliers weren't good in either spot, losing 45-17 as 1-point home faves against Georgia Tech.

Caesars hasn't moved off its Sunday opener of Louisville -20, but the total inched down to 51 this afternoon.

Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 11 Report containing spreads, lines, and trends for every Top 25 matchup.