College Football Odds Week 5: Alabama vs Mississippi State Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline

The college football Week 5 betting odds see the Alabama Crimson Tide favored by two touchdowns on the road over the Mississippi State Bulldogs in this SEC showdown. Coverage begins from Davis-Wade Stadium in Starkville, Mississippi on Saturday, September 30 at 9:00 p.m. ET on ESPN.

Here's everything you need to know about the college football odds for Week 5 Alabama vs. Mississippi State: the opening lines, spreads, betting trends and more. Check back regularly for updates.

No. 11 Alabama vs Mississippi State Odds

Jalen Milroe and Alabama are two-touchdown favorites in Week 5. (Getty)
  • Opening point spread: Alabama -14
  • Opening moneyline: Alabama -700/Mississippi State +500
  • Opening total: Over/Under 47 points scored
  • Time: 9 p.m. ET Saturday (ESPN)

UPDATE 6:45 P.M. ET SATURDAY: Alabama went from -14.5 to -14 and back to -14.5 by Tuesday at BetMGM Nevada. The Crimson Tide hit -15 Friday and went to -16 in the past hour, before quickly backing up to -15.5.

"There's sharp play on both sides of this game: Mississippi State +14.5 right when we opened, and as soon as we went to 14, sharp play on 'Bama -14," BetMGM Nevada's Scott Shelton said. "It's 4/1 tickets and money on Alabama."

The total initially climbed from 47.5 to 48.5 Sunday night, then spent the week toggling between 47.5 and 46.5. Then late this morning, the total dropped to 45.5 (Over -115).

"Really good two-way on tickets. Money approaching 3/1 on the Under. Sharp play on Under 47.5," Shelton said.

UPDATE 2:30 P.M. ET FRIDAY: This line toggled between 'Bama -14.5 and -14.0 early in the week at BetMGM. The Crimson Tide are now -14.5 (-115), with ticket count 5/1 and money 6/1 in favor of Alabama.

BetMGM's total went from 47.5 to 48.5 Sunday night. It then fell back to 46.5 Monday, climbed to 47.5 Wednesday and returned to 46.5 this morning. Tickets are running 5/1 and money 2/1 on the Under.

UPDATE 3 P.M. ET MONDAY: Alabama (3-1 SU/2-2 ATS) took care of Ole Miss 24-10 as 7-point home chalk in Week 4. Mississippi State (2-2 SU/1-3 ATS) lost at South Carolina 37-30 catching 6 points, the Bulldogs' third straight ATS setback.

Alabama nudged up to 14.5 shortly after opening Sunday in Caesars' college football odds Week 5 market. The total stretched to 48.5 within a couple of hours Sunday, then went to 48 this morning.

Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 5 Report containing spreads, lines, and trends for every Top 25 matchup.