College Football Odds Week 5: Iowa State vs Oklahoma Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline
Oklahoma vs
Iowa State
-20.5 (-110)
+20.5 (-110)
o48.5 (-110)
u48.5 (-110)
-1800
+750

Oklahoma is cruising through the Big 12 so far as the Sooners look to stay unbeaten at home against Iowa State. Coverage begins from Norman on Saturday, September 30 at 7:00 p.m. ET on FOX.

Here's everything you need to know about the college football odds for Week 5 Iowa State vs. Oklahoma: the opening lines, spreads, betting trends and more. Check back regularly for updates.

Iowa State vs No. 14 Oklahoma Odds

Oklahoma looks to keep rolling against Iowa State on Saturday. (Getty)
  • Opening point spread: Oklahoma -20
  • Opening moneyline: Oklahoma -1400/Iowa State +800
  • Opening total: Over/Under 48.5 points scored
  • Time: 7 p.m. ET Saturday (FS1)

UPDATE 2 P.M. ET FRIDAY: The Sooners are pinned to -20 at BetMGM, with the only adjustment coming this morning to -20 (-105). Oklahoma is now back at -20 flat, with tickets 2/1 and money 3/1 on big underdog Iowa State.

Likewise, the total hasn't moved off 48.5 so far. The Over is drawing 54% of bets, while 73% of cash is on the Under.

UPDATE 3 P.M. ET MONDAY: Oklahoma (4-0 SU and ATS) is among just five teams that remain perfect against the oddsmakers. The Sooners just barely covered the number in Week 4, beating Cincinnati 20-6 as 13.5-point favorites.

Iowa State (2-2 SU and ATS) halted a two-game SU and ATS hiccup with a 34-27 home win giving 3.5 points against Oklahoma State.

After opening at Sooners -20, Caesars initially backed up to -19 Sunday afternoon. By this morning, though, the number was up to Oklahoma -21.

Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 5 Report containing spreads, lines, and trends for every Top 25 matchup.