College Football Odds Week 5: LSU vs Mississippi Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline

A primetime battle in the SEC takes place in Week 5 of college football as LSU visits Mississippi. Both the Tigers and Rebels enter this contest owning 3-1 records as coverage begins from Vaught-Hemingway Stadium on Saturday, September 30 at 6:00 p.m. ET on ESPN.

Here's everything you need to know about the college football odds for Week 5 LSU vs. Mississippi: the opening lines, spreads, betting trends and more. Check back regularly for updates.

No. 13 LSU vs No. 20 Ole Miss Odds

LSU seeks its 4th straight win as the Tigers battle Ole Miss. (Getty)
  • Opening point spread: LSU -2.5
  • Opening moneyline: LSU -137/Ole Miss +112
  • Opening total: Over/Under 63.5 points scored
  • Time: 6 p.m. ET Saturday (ESPN)

UPDATE 5:55 P.M. ET SATURDAY: With kickoff approaching, LSU is up to -3 (-105) at BetMGM, after opening and spending most of the week at -2.5. Earlier today, BetMGM reported tickets were 2.5/1 and money 3/1 on the Tigers.

The total shot from 62.5 to 67.5 by Wednesday, then today dipped to 66.5 (Over -115). That noted, it was two-way action earlier today at BetMGM. The latest splits aren't available.

UPDATE 3 P.M. ET THURSDAY: The Tigers have spent most of the week toggling between -2.5 and -3 at PointsBet, save for a short stint Tuesday at -2. LSU is now -2.5 while taking 80% of spread bets/87% of spread dollars.

Some early bettors are eschewing the points and instead betting LSU moneyline, currently -140. Tickets are 3/1 and money beyond 9/1 on the Tigers.

PointsBet's total climbed from 63.5 to 67.5 by Wednesday afternoon. The Over is netting 61% of tickets/82% of money so far.

UPDATE 3 P.M. ET MONDAY: LSU (3-1 SU/2-2 ATS) narrowly avoided what would've been a devastating second loss of the season. Laying 17.5 points against visiting Arkansas, the Tigers needed a final-seconds field goal to win 34-31.

Mississippi (3-1 SU and ATS) won and cashed its first three, but had a tough Week 4 chore at Alabama. The Rebels lost 27-10 catching 7 points.

There's no early spread movement at TwinSpires. But ticket count is 2.5/1 and money 2/1 on the short road chalk Tigers.

"LSU is one of the more popular bets since we opened Week 5 games. LSU moneyline is already seeing 6/1 tickets and 7/1 money," Lucas said.

The total is down a half-point to 63, with 61% of bets on the Over/53% of money on the Under.

"Sharp play on Under 63.5," Lucas said.

Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 5 Report containing spreads, lines, and trends for every Top 25 matchup.