College Football Odds Week 6: Lines, Betting Trends on Biggest Games
College football odds for Week 6 are a big comedown from Week 5. There's nothing approaching Georgia vs. Alabama.
But there are still some important matchups in odds for college football Week 6. Missouri and Ole Miss face challenging foes in the SEC. And surprising UNLV hopes to continue making its case for the College Football Playoff Group of 5 bid.
Here’s everything you need to know about the college football odds Week 6 market: opening lines, spreads and betting trends for the biggest games, as multiple oddsmakers provide insights on college football Week 6 odds and action. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.
College Football Odds for Week 6
Syracuse vs. No. 25 UNLV
| Matchup | Spread | Total | Moneyline |
|---|---|---|---|
| UNLV vs
Syracuse | -6 (-105)
+6 (-115) | o59.5 (-110)
u59.5 (-110) | -225 +185 |
- Opening point spread: UNLV -4.5
- Opening moneyline: UNLV -205/Syracuse +165
- Opening total: Over/Under 58 points scored
- Time: 9 p.m. ET Friday (FS1)
UPDATE 5:30 P.M. ET MONDAY: No. 25 UNLV is out to a 4-0 SU and ATS start, which is unexpected to say the least. Particularly since starting quarterback Matt Sluka left the program last week in a Name/Image/Likeness money dispute.
But the Rebels didn't miss a beat behind QB Hajj-Malik Williams. In Week 5, UNLV closed as a 2.5-point home favorite vs. Fresno State and boatraced the Bulldogs 59-14.
Williams was an efficient 13 of 16 passing for 182 yards and three touchdowns, and he rushed for 119 yards and another TD.
The Rebels also have a 23-20 road win over Kansas to their credit, winning outright as 9-point underdogs. UNLV cracked the AP rankings this week for the first time in program history, sitting at No. 25.
Syracuse (3-1 SU/1-3 ATS) also rolled in Week 5, though against a lightweight FCS opponent. The Orange beat Holy Cross 42-14, just short of covering as 30.5-point home favorites.
TwinSpires Sportsbook opened Syracuse-UNLV at Rebels -4.5 and is already out to -6.5 in the college football odds Week 6 market. The line made stops at -5/-5.5 on the way up. UNLV is netting 60% of early spread tickets/77% of early spread money.
"It's a mix of public and sharp play on UNLV. We may move to 7 to get some money back on Syracuse," TwinSpires director of retail sports Zachary Lucas said.
The Rebels are also nabbing 78% of tickets/82% of cash on the moneyline. The total is up a tick from 58 to 58.5, with 63% of tickets/59% of cash on the Over.
Missouri vs. Texas A&M Odds
| Matchup | Spread | Total | Moneyline |
|---|---|---|---|
| Texas A&M vs
Missouri | -2 (-108)
+2 (-112) | o48.5 (-110)
u48.5 (-110) | -125 +105 |
- Opening point spread: Texas A&M -2.5
- Opening moneyline: Texas A&M -135/Missouri +115
- Opening total: Over/Under 49.5 points scored
- Time: Noon ET Saturday (ABC)
UPDATE 4 P.M. ET MONDAY: No. 9 Missouri (4-0 SU/2-2 ATS) is coming off a bye week, which it probably needed after a huge Week 4 scare. The Tigers closed as 18.5-point home favorites vs. Vanderbilt and escaped with a 30-27 double-overtime win.
No. 25 Texas A&M (4-1 SU/1-4 ATS) lost its season opener at home vs. Notre Dame. But the Aggies followed with four straight wins. In Week 5, A&M held off Arkansas 21-17, but failed to cover as 6.5-point neutral-site chalk at AT&T Stadium.
TwinSpires Sportsbook opened the Aggies -2.5 vs. the Tigers. The line fell to -1.5, rebounded to -2 and is now -1.5 again. Missouri is landing 66% of early spread tickets/63% of early spread money.
On the moneyline, the Tigers are taking 70% of early tickets/58% of early cash.
"Mizzou is shaping up to be a public 'dog. Unless something drastic happens, we'll need the Aggies," TwinSpires director of retail sports Zachary Lucas said.
The total is down a point to 48.5, with 61% of tickets/52% of money on the Over.
Iowa vs. Ohio State Odds
| Matchup | Spread | Total | Moneyline |
|---|---|---|---|
| Ohio State vs
Iowa | -19.5 (-110)
+19.5 (-110) | o44.5 (-110)
u44.5 (-110) | -1200 +750 |
- Opening point spread: Ohio State -20.5
- Opening moneyline: Ohio State -2500/Iowa +1050
- Opening total: Over/Under 44.5 points scored
- Time: 3:30 p.m. ET Saturday (CBS)
UPDATE 4 P.M. ET MONDAY: No. 3 Ohio State (4-0 SU/2-2 ATS) looks to stay on track in the Big Ten and the CFP race. In Week 5, the Buckeyes drilled Michigan State 38-7 laying 23.5 points at home.
Here's a shocker for Iowa: The Over has hit in all four games this season, aided by the Hawkeyes breaking the 30-point barrier three times. Iowa (3-1 SU/2-2 ATS) had a bye in Week 5, after notching a 31-14 win at Minnesota as 3-point chalk.
TwinSpires Sportsbook opened Iowa-Ohio State at Buckeyes -20.5, and it just backed up to -19.5 in college football week 6 odds. The Hawkeyes are attracting 63% of early spread bets/67% of early spread money.
"Bettors are taking the insurance and expecting a close game here for Iowa. We'll gladly take that action at +20.5," TwinSpires director of retail sports Zachary Lucas said.
The total opened at 44.5, moved to 45.5, then returned to 44.5. The Over is getting 55% of tickets/60% of money.
Ole Miss vs. South Carolina Odds
| Matchup | Spread | Total | Moneyline |
|---|---|---|---|
| South Carolina vs
Ole Miss | +9.5 (-110)
-9.5 (-110) | o53 (-110)
u53 (-110) | +260 -325 |
- Opening point spread: Ole Miss -9
- Opening moneyline: Ole Miss -350/South Carolina +270
- Opening total: Over/Under 51.5 points scored
- Time: 3:30 p.m. ET Saturday (ESPN)
UPDATE 4 P.M. ET MONDAY: No. 12 Ole Miss (4-1 SU and ATS) is coming off a shocking loss that could leave little margin for error to earn a CFP bid. The Rebels were stifled throughout by Kentucky and lost 20-17 as 15-point home favorites.
Mississippi missed a 48-yard field goal with 48 seconds remaining.
South Carolina (3-1 SU and ATS) hammered that same Kentucky team 31-6 as a 9.5-point road underdog in Week 2. In Week 3, the Gamecocks had LSU on the ropes with a 24-10 lead, but ultimately fell just short as 6-point home pups, losing 36-33.
In Week 4, South Carolina rolled over Akron 50-7 laying 24.5 points at home. The Gamecocks had a bye in Week 5.
TwinSpires opened Ole Miss -9 vs. South Carolina and is up to -9.5 (-115). The Gamecocks are drawing 65% of early spread bets, while 59% of early spread money is on the Rebels.
"The public thinks this is too many points, based off what Ole Miss did last week. Sharps disagree and took Ole Miss -9," TwinSpires director of retail sports Zachary Lucas said.
The total rose from 51.5 to 52.5, with 69% of bets/63% of money on the Over.
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