College Football Odds Week 7: USC vs Notre Dame Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

1 minute read

Two old rivals hook up in South Bend for a primetime battle as Notre Dame hosts USC. Betting odds have the Fighting Irish as slight 2.5-point favorites against the Trojans under the lights. Coverage begins from Notre Dame Stadium on Saturday, October 14 at 7:30 p.m. ET on NBC.

Here's everything you need to know about the college football odds for Week 7 USC vs Notre Dame: the opening lines, spreads, betting trends and more. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

No. 10 USC vs No. 21 Notre Dame Odds

• Opening point spread: Notre Dame -2.5
• Opening moneyline: Notre Dame -130/USC +107
• Opening total: Over/Under 63 points scored
• Time: 7:30 p.m. ET Saturday (NBC)

UPDATE 2:30 P.M. ET THURSDAY: Notre Dame has bounced between various iterations of -2.5 and -3 all week at PointsBet. The Fighting Irish are now -2.5 (-115) on two-way action with a lean toward USC. The Trojans are netting 53% of early tickets/55% of early cash.

PointsBet's total opened at 62.5 and peaked at 63 multiple times early in the week. It's now down to 60.5 (Under -115), although tickets and money are in the 3/1 range on the Over.

UPDATE MIDNIGHT ET MONDAY: USC (6-0 SU/2-4 ATS) remained unbeaten, but barely so in a Week 6 game it was supposed to win with ease. The Trojans closed as 21-point home faves against Arizona and fell into a 17-0 hole by early in the second quarter.

Southern Cal scrambled to take a 28-20 lead. But Arizona tied it at 28 midway through the fourth quarter, and the Trojans got dragged into overtime. USC ultimately prevailed 43-41 in triple OT.

Notre Dame would've gladly accepted an overtime win at Louisville, but got nothing of the sort. The Fighting Irish (5-2 SU and ATS) lost 33-20 as 6.5-point favorites.

TwinSpires opened Notre Dame -2.5 and is down to -2 early in the week. USC is taking 59% of early tickets and cash on the spread.

"At 6-0, USC is a trendy 'dog. But we've seen this spot last week, when numerous public 'dogs didn't cover – Mizzou, Maryland and Kentucky," Lucas said.

The total steamed from 63 to 61 early, but has already rebounded to the 63 opener.

"Sharp play on Under 63," Lucas said.

Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 7 Report containing spreads, lines, and trends for every Top 25 matchup.

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson