College Football Odds Week 9: Duke vs Louisville Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

2 minute read

Both Duke and Louisville are coming off road losses in their last games as the two ACC squads meet up in Week 9 of college football. Betting odds see the Cardinals as 4.5-point home favorites against the Blue Devils. Coverage begins from L&N Federal Credit Union Stadium on Saturday, October 28 at 3:30 p.m. ET on ESPN.

Here's everything you need to know about the college football odds for Week 9 Duke vs Louisville: the opening lines, spreads, betting trends and more. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

No. 20 Duke vs No. 18 Louisville Odds

• Opening point spread: Louisville -4
• Opening moneyline: Louisville -167/Duke +135
• Opening total: Over/Under 47 points scored
• Time: 3:30 p.m. ET Saturday (ESPN)

UPDATE 1 P.M. ET SATURDAY: Caesars Sports opened Louisville -3 on Sunday afternoon, quickly went to -3.5, then got to -4 within a couple hours. On Thursday, the Cardinals got to -4.5, then Friday stretched out to -6.

It's still -6, with ticket count almost even and 60% of money on Louisville.

The total went from 47 to 48 Monday, but quickly receded to 46. It toggled between 46 and 46.5 the past few days, then dipped to 45.5 Friday and 45 today. Current Caesars splits aren't available.

UPDATE 5 P.M. ET THURSDAY: Louisville opened -4 Sunday at PointsBet, then late this morning adjusted to -4 (-115) on the way to -4.5. However, underdog Duke is landing 54% of early bets/61% of early money.

The total rose from 47 to 48 (Under -120) briefly Monday afternoon, then quickly dropped to 46.5. The Over has 78% of bets, and 61% of money is on the Under.

UPDATE 3 P.M. ET MONDAY: Duke (5-2 SU/4-3 ATS) had the opportunity to pull off a massive upset, but couldn't hold down Florida State in the fourth quarter. The Blue Devils got out to a 10-0 first-quarter lead and were up 20-17 at halftime of the Week 8 ACC clash.

After a scoreless third quarter, Duke gave up the final 21 points of the game, losing 38-20 as a 14-point road pup.

Louisville (6-1 SU/3-3-1 ATS) is coming off a bye it probably needed after an upset loss at Pittsburgh. The Cardinals, laying 7 points, led 21-14 at halftime but didn't score again in a 38-21 Week 7 setback.

TwinSpires opened Louisville -4 and moved to -4.5 in its college football odds Week 9 market. The Cardinals then returned to -4 this afternoon, while landing 63% of early spread bets/72% of early spread cash.

"It's a mix of sharp and public play on Louisville -4. Our sportsbook across the street from the stadium will be lined up full of Cardinals bettors," Lucas said.

The total initially went from 47 to 47.5 and is now 46.5, though the Over is taking 57% of tickets/64% of money.

Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 9 Report containing spreads, lines, and trends for every Top 25 matchup.

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson