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Featured Last Updated Oct 14 2025, 4:17 PM

LSU vs. Vanderbilt: Prediction, Odds, Best Bet

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
8 minute read
LSU vs. Vanderbilt: Prediction, Odds, Best Bet

Image Credit: David Leong-Imagn Images

LSU @ VAN Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
LSU Tigers 365 LSU
-3.5 -110 +0.5 -115 + +0.5 -115 + +0.5 -112 + +0.5 -115 + +0.5 -125 + +1.5 -134 + +0.5 -120 + +0.5 -120 +1.5 -121 + +1.5 -105  
Vanderbilt Commodores 366 Vanderbilt
+3.5 -110 -0.5 -105 + -0.5 -105 + -0.5 -108 + -0.5 -105 + -0.5 -105 + -1.5 +110 + -0.5 even + -0.5 even -1.5 -103 + -1.5 -115  
LSU Tigers 365 LSU
o49.5 -105 o23.5 -115 + N/A o23.5 -110 + o23.5 -115 + N/A o24.5 +112 + o23.5 -115 + o23.5 -115 o23.5 -115 + o48.5 -105  
Vanderbilt Commodores 366 Vanderbilt
u49.5 -115 u23.5 -105 + N/A u23.5 -110 + u23.5 -105 + N/A u24.5 -138 + u23.5 -105 + u23.5 -105 u23.5 -120 + u48.5 -115  
LSU Tigers 365 LSU
-102 even + even + +105 + even + -105 + -102 + N/A N/A even + +102  
Vanderbilt Commodores 366 Vanderbilt
-118 -120 + -120 + -125 + -120 + -125 + -120 + N/A N/A -129 + -122  
LSU Tigers 365 LSU
-3.5 -110 +0.5 -135 + +0.5 -150 + +0.5 -140 + +0.5 -140 + +0.5 -150 + +1.5 -180 + +0.5 -150 + -0.5 +155 +1.5 -175 + +1.5 -105  
Vanderbilt Commodores 366 Vanderbilt
+3.5 -110 -0.5 +115 + -0.5 +118 + -0.5 +110 + -0.5 +110 + -0.5 +120 + -1.5 +142 + -0.5 +115 + +0.5 -220 -1.5 +133 + -1.5 -115  
LSU Tigers 365 LSU
o49.5 -105 o10.5 +105 + N/A o10.5 +105 + o10 -125 + o10.5 +110 + o9.5 -150 + o10.5 +105 + o10.5 +110 o9.5 -127 + o48.5 -105  
Vanderbilt Commodores 366 Vanderbilt
u49.5 -115 u10.5 -135 + N/A u10.5 -135 + u10 -105 + u10.5 -140 + u9.5 +118 + u10.5 -135 + u10.5 -150 u9.5 -104 + u48.5 -115  
LSU Tigers 365 LSU
-102 even + +105 + +105 + even + -110 + -113 + N/A N/A -106 + +102  
Vanderbilt Commodores 366 Vanderbilt
-118 -120 + -135 + -135 + -130 + -120 + -113 + N/A N/A -124 + -122  
LSU Tigers 365 LSU
-3.5 -110 N/A N/A +1.5 -142 + -0.5 +105 + N/A N/A N/A N/A N/A +1.5 -105  
Vanderbilt Commodores 366 Vanderbilt
+3.5 -110 N/A N/A -1.5 +120 + +0.5 -125 + N/A N/A N/A N/A N/A -1.5 -115  
LSU Tigers 365 LSU
o49.5 -105 N/A N/A o24.5 +102 + o23.5 -125 + N/A N/A o23.5 -130 + N/A N/A o48.5 -105  
Vanderbilt Commodores 366 Vanderbilt
u49.5 -115 N/A N/A u24.5 -122 + u23.5 +105 + N/A N/A u23.5 even + N/A N/A u48.5 -115  
LSU Tigers 365 LSU
-102 N/A N/A -112 + N/A N/A N/A N/A N/A N/A +102  
Vanderbilt Commodores 366 Vanderbilt
-118 N/A N/A -108 + N/A N/A N/A N/A N/A N/A -122  
LSU Tigers 365 LSU
-3.5 -110 N/A N/A +0.5 -154 + N/A N/A +1.5 -158 + +0.5 -160 + N/A N/A +1.5 -105  
Vanderbilt Commodores 366 Vanderbilt
+3.5 -110 N/A N/A -0.5 +120 + N/A N/A -1.5 +118 + -0.5 +120 + N/A N/A -1.5 -115  
LSU Tigers 365 LSU
o49.5 -105 o14 -110 + N/A o12.5 -125 + N/A N/A o13.5 -122 + o13.5 -110 + N/A N/A o48.5 -105  
Vanderbilt Commodores 366 Vanderbilt
u49.5 -115 u14 -110 + N/A u12.5 -105 + N/A N/A u13.5 -102 + u13.5 -120 + N/A N/A u48.5 -115  
LSU Tigers 365 LSU
-102 -105 + N/A -115 + N/A N/A -104 + N/A N/A N/A +102  
Vanderbilt Commodores 366 Vanderbilt
-118 -115 + N/A -115 + N/A N/A -122 + N/A N/A N/A -122  
LSU Tigers 365 LSU
-3.5 -110 N/A N/A -0.5 +130 + N/A N/A +1.5 -180 + -0.5 +140 + N/A N/A +1.5 -105  
Vanderbilt Commodores 366 Vanderbilt
+3.5 -110 N/A N/A +0.5 -166 + N/A N/A -1.5 +130 + +0.5 -180 + N/A N/A -1.5 -115  
LSU Tigers 365 LSU
o49.5 -105 o10 -110 + N/A o9.5 -140 + N/A N/A o9.5 -150 + o9.5 -125 + N/A N/A o48.5 -105  
Vanderbilt Commodores 366 Vanderbilt
u49.5 -115 u10 -110 + N/A u9.5 +110 + N/A N/A u9.5 +120 + u9.5 -105 + N/A N/A u48.5 -115  
LSU Tigers 365 LSU
-102 -105 + N/A -120 + N/A N/A -100 + N/A N/A N/A +102  
Vanderbilt Commodores 366 Vanderbilt
-118 -115 + N/A -110 + N/A N/A -128 + N/A N/A N/A -122  
LSU Tigers 365 LSU
-3.5 -110 +0.5 -165 + N/A +0.5 -145 + N/A N/A +1.5 -178 + -0.5 +130 + N/A N/A +1.5 -105  
Vanderbilt Commodores 366 Vanderbilt
+3.5 -110 -0.5 +145 + N/A -0.5 +114 + N/A N/A -1.5 +128 + +0.5 -170 + N/A N/A -1.5 -115  
LSU Tigers 365 LSU
o49.5 -105 o13.5 -110 + N/A o13.5 -130 + N/A N/A o12.5 -120 + o13.5 -140 + N/A N/A o48.5 -105  
Vanderbilt Commodores 366 Vanderbilt
u49.5 -115 u13.5 -110 + N/A u13.5 even + N/A N/A u12.5 -104 + u13.5 +110 + N/A N/A u48.5 -115  
LSU Tigers 365 LSU
-102 -110 + N/A -115 + N/A N/A -106 + N/A N/A N/A +102  
Vanderbilt Commodores 366 Vanderbilt
-118 -110 + N/A -115 + N/A N/A -120 + N/A N/A N/A -122  

The LSU Tigers will take on the Vanderbilt Commodores in this week's college football action. Kickoff is set for 12:00 p.m. EDT at FirstBank Stadium in Nashville, Tenn. The game will be broadcast live on ABC. Here's everything you need to know about LSU vs. Vanderbilt odds, the latest college football spreads, college football over/unders and more.

The Vanderbilt Commodores opened as a -2.5 point favorite over LSU. The total is set at over/under 48.5 total points scored by both teams combined.

This game is featured in our college football week 8 best bets article. Check out the rest of my bets for saturday.

Be sure to check out the latest college football odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 10/17/25

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LSU vs. Vanderbilt Best Bet

While LSU's offense is having its offensive struggles, their defense has been extremely strong. This combination has led LSU to a 5-1 record to the under. Neither team is in a rush to get plays off, and even Vanderbilt's defense has flashed some promise. I am going to bet on LSU to continue their defensive dominance and offensive ineptitude.

LSU vs. Vanderbilt Best Bet: LSU Tigers @ Vanderbilt Commodores u49.5 (-112)


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(Pick from Dylan Wilkerson)

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What Time is the Vanderbilt vs. LSU Game?

The Commodores will take on the Tigers at 12:00 PM ET on Saturday, October 18th.

Where is the Vanderbilt vs. LSU Game Being Played?

This game is going to be played at FirstBank Stadium in Nashville, Tenn.

How Can I Watch The Vanderbilt vs. LSU Game?

You can watch Vanderbilt vs. LSU on ABC.

Can LSU Beat The Vanderbilt Commodores?

Absolutely! LSU is a slight underdog in this game. Anything can happen in college football!

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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