2022 Iowa State Cyclones Betting Odds, Picks & Predictions

2022 IOWA STATE CYCLONES BETTING ODDS, PREDICTIONS, PREVIEW

Matt Campbell is already the greatest head coach in Iowa State history. His .553 winning percentage is the best in school history, and he has taken the Cyclones to five bowl games in six seasons. Campbell has the second-most wins behind only Dan McCarney, and Campbell has 42 wins in six years compared to 56 wins in 12 years for McCarney.

Campbell has been linked to multiple Big Ten jobs over the last few years, but he has continually opted to stay put in Ames. That has earned him the love of the boosters and the administration, as the Cyclones were a perennial bottom feeder in the Big 12 prior to his arrival. He has a tough job ahead of him this year though, as a lot of the players that were program leaders have now moved on, and only eight starters return from last year’s squad.

Most of the offensive production from the last few seasons is gone. Brock Purdy and Breece Hall are now in the NFL, and four of the five top receivers from 2021 are no longer on the roster. Redshirt freshman Hunter Dekkers has his work cut out for him replacing Purdy, but he saw a little bit of action last year and Campbell has expressed confidence in the four-star prospect.

Jirehl Brock will likely replace Hall as the workhorse running back in this offense. Brock has spent three years with the Cyclones, and he was the third-leading rusher behind Hall and Purdy last season. Keep an eye on true freshman Cartevious Norton though, as he impressed in spring practice.

This offensive line is in good shape with First Team All-Big 12 selection Trevor Downing up front. Darrell Simmons earned all-conference honors last year too, and they will be the anchors of this unit.  It will be one of the youngest units in the conference though as four underclassmen are currently projected to start.

Updated on 12/24/2024

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First Team All-Big 12 receiver Xavier Hutchinson will be the star of this offense in 2022. Hutchinson had 83 receptions for 987 yards and five touchdowns last season, and the only other receiver that saw a decent amount of action is Jaylin Noel.

Iowa State’s defense loses standout linebacker Mike Rose. Rose was the Big 12 Defensive Player of the Year in 2020 and a two-time First Team All-Big 12 selection in 2020 and 2021. However, the Cyclones still have their First Team All-Big 12 defensive end in Will McDonald IV. McDonald is one of the best pass rushers in the country, and there will be more pressure on him than ever as he is one of just three returning starters on defense.

This is a big season for Matt Campbell. If the Cyclones can be bowl eligible once again, then he will be even more sought after by other programs. Iowa State lost a lot of leadership this year, and he can prove that it wasn’t just one special recruiting class.

Trust the process. Campbell has shown that he can win in Ames, and the Cyclones should win two of their three non-conference games. This team was very unlucky to finish 7-6 last year considering the Cyclones ranked 19^th in SP+, so they should have a winning record if some of that luck evens out in 2022.

Best Bet: Over 6.5 Wins (-115)

2022 IOWA STATE CYCLONES SCHEDULE

• Sat., Sept. 3 - vs. SE Missouri State
• Sat., Sept. 10 - at Iowa
• Sat., Sept. 17 - vs. Ohio
• Sat., Sept. 24 - vs. Baylor
• Sat., Oct. 1 - at Kansas
• Sat., Oct. 8 - vs. Kansas State
• Sat., Oct. 15 - at Texas
• Sat., Oct. 29 - vs. Oklahoma
• Sat., Nov. 5 - vs. West Virginia
• Sat., Nov. 12 - at Oklahoma State
• Sat., Nov. 19 - vs. Texas Tech
• Sat., Nov. 26 - at TCU

WIN TOTAL ODDS

• Over 6.5 (-115)
• Under 6.5 (-115)

IOWA STATE CYCLONES ODDS TO WIN BIG 12 CHAMPIONSHIP

+1800

This is a bit too much to ask for such a young team. The Cyclones were a legitimate Big 12 contender for the last two seasons, but there are too many questions at too many key positions. Iowa State hasn’t won a conference title in over 100 years at this point, and that wait won’t end this year.

IOWA STATE CYCLONES ODDS TO WIN NATIONAL CHAMPIONSHIP

+12500

The Cyclones have never won 10 games in a season, and they have only won nine games three times in their 125-year history. That highlights just how good of a job that Campbell has done, and it also underscores that this program is not a national title contender.

IOWA STATE CYCLONES 2022 HEISMAN CONTENDERS & ODDS

The Iowa State Cyclones do not have any Heisman contenders to begin the 2022 season.

2021 IOWA STATE CYCLONES BETTING RESULTS

• SU: 7-6
• ATS: 5-8
• O/U: 6-7
• ATS-Home: 3-4
• ATS-Road: 2-4
• ATS-Favorite: 5-6
• ATS-Underdog: 0-2

MORE CONFERENCE ODDS