James Madison Dukes Odds
| Date | Opp | Close | Result | ATS/OU |
| Aug 30, 2025 | Weber State | -
/ | | 12:00 PM ET |
| Sep 5, 2025 | @Louisville | -
/ | | 12:00 PM ET |
| Sep 20, 2025 | @Liberty | -
/ | | 12:00 PM ET |
| Sep 27, 2025 | Georgia Southern | -
/ | | 12:00 PM ET |
| Oct 4, 2025 | @Georgia State | -
/ | | 12:00 PM ET |
| Oct 11, 2025 | Louisiana | -
/ | | 12:00 PM ET |
| Oct 18, 2025 | Old Dominion | -
/ | | 12:00 PM ET |
| Oct 28, 2025 | @Texas State | -
/ | | 12:00 PM ET |
| Nov 8, 2025 | @Marshall | -
/ | | 1:00 PM ET |
| Nov 15, 2025 | Appalachian State | -
/ | | 1:00 PM ET |
| Nov 22, 2025 | Washington State | -
/ | | 1:00 PM ET |
| Nov 29, 2025 | @Coastal Carolina | -
/ | | 1:00 PM ET |
