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USC vs. Michigan Odds: Trojans Favorites in College Football Week 4 Lines

Patrick Everson
Patrick Everson Sports Betting Expert
3 minute read
USC vs. Michigan Odds: Trojans Favorites in College Football Week 4 Lines

🚨UPDATE 2:45 P.M. ET SATURDAY: Forty-five minutes before kickoff, the Trojans are -4.5 in BetMGM's odds for USC vs. Michigan. Last Sunday, USC opened -6.5, and the line spent the week bouncing between the opener and -6/-5.5.

Friday brought moves to Southern Cal -5 and -4.5. In digital betting (online/mobile), spread ticket count is 3/1 and spread money 2/1 on USC.

"Sharps love Michigan. But we are still gonna need Michigan covering 4.5 to 6. And Michigan outright is great for us," BetMGM trading manager Seamus Magee.

The total opened at 45.5 and initially climbed to 46.5 Sunday night. But the number dropped to 44.5 Wednesday and has been at 44 (Over -115) since Friday night. The Over is seeing 60% of tickets/73% of money.

🚨UPDATE 4 P.M. ET FRIDAY: USC is down to a 4.5-point favorite in its Big Ten debut. The Trojans opened at -6.5 and spent time at -5.5 in Fanatics Sportsbook's USC vs. Michigan odds market.

Contrary to the dip, both point-spread and moneyline dollars are strongly on USC. Spread cash is running 80/20 and moneyline dollars 83/17 in favor of the Trojans.

"It's interesting, because the Michigan faithful are kind of going against their own here," Fanatics college football trader Ty Gour said, noting the Michigan market – a big one for Fanatics – usually has strong regional bias.

But not this week, in Michigan or the many other states Fanatics operates in.

"People are liking what they're seeing from USC, and for Michigan, there are more questions than answers right now," Gour said.

Fanatics' total has bounced around quite a bit, from a high of 47.5 to a low of 43.5. It's now at 44.

---

USC vs. Michigan odds might make you think of a Rose Bowl matchup. But no, this is still September. Oh, and USC is now in the Big Ten with Michigan, to make things even more confusing.

Southern Cal heads to Ann Arbor as a favorite in odds for USC Trojans vs. Michigan Wolverines. Defending national champion and 18th-ranked Michigan already has one home loss, to Texas, and can't afford another to No. 11 USC.

Here's everything you need to know about USC vs. Michigan odds: opening lines, spreads and betting trends on the game, as multiple oddsmakers provide insights on college football Week 4 odds and action.

Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

USC vs. Michigan Live Odds

🏈 USC vs Michigan🤑 Spread💸 Moneyline 📈 Total
USC-5.5 (-110)-210O 44 (-110)
Michigan+5.5 (-110)+175U 44 (-110)
Based on Consensus - Subject to Change

USC vs. Michigan Line Moves, Betting

Michigan coach Sherrone Moore faces another tough test vs. USC. (Getty)

USC @ MICH Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Final
USC Trojans 387 USC
+11 -110 -3 -105 -3 even -2.5 -120 -3 -105 -2.5 -120 -1.5 -106 -1.5 -112 -2.5 -115 -5.5 -115  
Michigan Wolverines 388 Michigan
-11 -110 +3 -115 +3 -120 +2.5 -110 +3 -115 +2.5 even +1.5 -114 +1.5 -120 +2.5 -113 +5.5 -115  
Final
USC Trojans 387 USC
o47 -110 o21.5 even N/A o22.5 -125 o21.5 even N/A o21.5 -108 o21.5 -104 o21.5 -103 o44.5 -110  
Michigan Wolverines 388 Michigan
u47 -110 u21.5 -120 N/A u22.5 -105 u21.5 -120 N/A u21.5 -112 u21.5 -129 u21.5 -127 u44.5 -120  
Final
USC Trojans 387 USC
-238 -170 -165 -160 -170 -160 -142 -167 -159 -220  
Michigan Wolverines 388 Michigan
+195 +145 +140 +124 +143 +125 +116 +120 +120 +170  
Final
USC Trojans 387 USC
+11 -110 N/A N/A -3.5 -105 N/A N/A N/A N/A N/A -5.5 -115  
Michigan Wolverines 388 Michigan
-11 -110 N/A N/A +3.5 -125 N/A N/A N/A N/A N/A +5.5 -115  
Final
USC Trojans 387 USC
o47 -110 N/A N/A o20.5 -120 N/A N/A N/A N/A N/A o44.5 -110  
Michigan Wolverines 388 Michigan
u47 -110 N/A N/A u20.5 -110 N/A N/A N/A N/A N/A u44.5 -120  
Final
USC Trojans 387 USC
-238 N/A N/A -200 N/A N/A N/A N/A N/A -220  
Michigan Wolverines 388 Michigan
+195 N/A N/A +154 N/A N/A N/A N/A N/A +170  
Final
USC Trojans 387 USC
+11 -110 -0.5 -115 -0.5 -110 -0.5 +120 -0.5 even -0.5 even -1.5 +138 -1.5 +114 -1.5 +114 -5.5 -115  
Michigan Wolverines 388 Michigan
-11 -110 +0.5 -115 +0.5 -120 +0.5 -154 +0.5 -120 +0.5 -130 +1.5 -174 +1.5 -165 +1.5 -152 +5.5 -115  
Final
USC Trojans 387 USC
o47 -110 o10 -110 N/A o9.5 -120 o9.5 -120 o9.5 -125 o8.5 -112 o9.5 -121 o9.5 -120 o44.5 -110  
Michigan Wolverines 388 Michigan
u47 -110 u10 -120 N/A u9.5 -110 u9.5 even u9.5 -105 u8.5 -112 u9.5 -110 u9.5 -109 u44.5 -120  
Final
USC Trojans 387 USC
-238 -165 -165 -125 -160 -170 -122 -148 -148 -220  
Michigan Wolverines 388 Michigan
+195 +135 +130 -105 +135 +135 -104 +112 +114 +170  
Final
USC Trojans 387 USC
+11 -110 N/A N/A -2.5 -120 N/A N/A -1.5 +102 N/A N/A -5.5 -115  
Michigan Wolverines 388 Michigan
-11 -110 N/A N/A +2.5 -110 N/A N/A +1.5 -128 N/A N/A +5.5 -115  
Final
USC Trojans 387 USC
o47 -110 N/A N/A o13.5 +105 N/A N/A o14.5 +112 N/A N/A o44.5 -110  
Michigan Wolverines 388 Michigan
u47 -110 N/A N/A u13.5 -135 N/A N/A u14.5 -146 N/A N/A u44.5 -120  
Final
USC Trojans 387 USC
-238 N/A N/A -180 N/A N/A -150 N/A N/A -220  
Michigan Wolverines 388 Michigan
+195 N/A N/A +140 N/A N/A +118 N/A N/A +170  
Final
USC Trojans 387 USC
+11 -110 N/A N/A -0.5 -110 N/A N/A -1.5 -110 N/A N/A -5.5 -115  
Michigan Wolverines 388 Michigan
-11 -110 N/A N/A +0.5 -120 N/A N/A +1.5 -114 N/A N/A +5.5 -115  
Final
USC Trojans 387 USC
o47 -110 N/A N/A o7.5 -115 N/A N/A o14.5 +104 N/A N/A o44.5 -110  
Michigan Wolverines 388 Michigan
u47 -110 N/A N/A u7.5 -115 N/A N/A u14.5 -135 N/A N/A u44.5 -120  
Final
USC Trojans 387 USC
-238 N/A N/A -175 N/A N/A -210 N/A N/A -220  
Michigan Wolverines 388 Michigan
+195 N/A N/A +135 N/A N/A +162 N/A N/A +170  
Final
USC Trojans 387 USC
+11 -110 N/A N/A -1.5 -115 N/A N/A -1.5 +124 N/A N/A -5.5 -115  
Michigan Wolverines 388 Michigan
-11 -110 N/A N/A +1.5 -115 N/A N/A +1.5 -156 N/A N/A +5.5 -115  
Final
USC Trojans 387 USC
o47 -110 N/A N/A o12.5 -120 N/A N/A o10.5 -100 N/A N/A o44.5 -110  
Michigan Wolverines 388 Michigan
u47 -110 N/A N/A u12.5 -110 N/A N/A u10.5 -124 N/A N/A u44.5 -120  
Final
USC Trojans 387 USC
-238 N/A N/A -175 N/A N/A -136 N/A N/A -220  
Michigan Wolverines 388 Michigan
+195 N/A N/A +135 N/A N/A +106 N/A N/A +170  
  • Opening point spread: USC -6
  • Opening moneyline: USC -225/Michigan +190
  • Opening total: Over/Under 46.5 points scored
  • Time: 3:30 p.m. ET Saturday (CBS)

USC is already coming off a bye, taking Week 3 off after opening 2-0 SU and ATS. In Week 1, the Trojans notched an impressive 27-20 win catching 4 points against LSU, in a neutral-site game in Las Vegas.

Southern Cal followed with a much easier 48-0 rout of Utah State, with USC giving 31 points at home.

Michigan got flattened by Texas in Week 2, losing 31-12 as 6.5-point road underdogs. In Week 3, the Wolverines had Arkansas State in a 28-3 hole early in the fourth quarter, then let off the gas. Michigan won 28-18, but didn't cash as a 21.5-point home favorite.

TwinSpires Sportsbook opened the Trojans -5.5 and moved to -6 on the USC vs. Michigan odds board. On Thursday afternoon, the line is back at Southern Cal -5.5, with 75% of early spread tickets/82% of early spread money on the Trojans.

"It feels like nobody wants to back Michigan after the Week 2 performance vs. Texas. We'll be big fans of the Wolverines to at least get a cover for us," TwinSpires director of retail sports Zachary Lucas said.

The total opened at 46 and is down to 44.5, with a stop at 45 on the way. The Under is seeing 59% of tickets/52% of money.

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Patrick Everson

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson
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