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Featured Last Updated Oct 3 2025, 10:42 AM

Washington Commanders vs. Los Angeles Chargers Week 5 Prediction: Odds, Best Bet

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
8 minute read
Washington Commanders vs. Los Angeles Chargers Week 5 Prediction: Odds, Best Bet

Washington Commanders vs. Los Angeles Chargers Odds, NFL Week 5

Image Credit: Junfu Han / USA TODAY NETWORK via Imagn Images

WAS @ LAC Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Washington Commanders 481 Commanders
+1.5 -115 +1.5 -105 + +1.5 -115 + +1.5 -115 + +1.5 -105 + +2.5 -110 + +1.5 -120 + +1.5 -110 + +1.5 -110 +1.5 -118 + +3 -120  
Los Angeles Chargers 482 Chargers
-1.5 -105 -1.5 -115 + -1.5 -105 + -1.5 -105 + -1.5 -115 + -2.5 -120 + -1.5 -100 + -1.5 -110 + -1.5 -110 -1.5 -106 + -3 even  
Washington Commanders 481 Commanders
o47.5 -112 o23.5 -120 + N/A o24.5 -105 + o23.5 -110 + N/A o23.5 -110 + o23.5 -110 + o22.5 -145 o23.5 -113 + o48.5 -115  
Los Angeles Chargers 482 Chargers
u47.5 -108 u23.5 even + N/A u24.5 -115 + u23.5 -110 + N/A u23.5 -110 + u23.5 -110 + u22.5 +120 u23.5 -112 + u48.5 -105  
Washington Commanders 481 Commanders
+102 +125 + N/A +114 + +122 + +130 + +112 + N/A +120 +114 + +130  
Los Angeles Chargers 482 Chargers
-122 -150 + N/A -135 + -145 + -170 + -138 + N/A -145 -141 + -155  
Washington Commanders 481 Commanders
+1.5 -115 +0.5 -130 + +0.5 -160 + +0.5 -148 + +0.5 -135 + +0.5 -130 + +1.5 -160 + +0.5 -135 + +1.5 -155 +1.5 -159 + +3 -120  
Los Angeles Chargers 482 Chargers
-1.5 -105 -0.5 +110 + -0.5 +125 + -0.5 +124 + -0.5 +105 + -0.5 even + -1.5 +128 + -0.5 +115 + -1.5 +115 -1.5 +128 + -3 even  
Washington Commanders 481 Commanders
o47.5 -112 o9.5 -115 + N/A o9.5 -122 + o9.5 -125 + o9.5 -115 + o8.5 -116 + o9.5 -110 + o8.5 -135 o9.5 -122 + o48.5 -115  
Los Angeles Chargers 482 Chargers
u47.5 -108 u9.5 -105 + N/A u9.5 +105 + u9.5 -105 + u9.5 -115 + u8.5 -106 + u9.5 -110 + u8.5 even u9.5 -103 + u48.5 -105  
Washington Commanders 481 Commanders
+102 +120 + N/A +105 + +110 + +125 + +108 + N/A +115 +107 + +130  
Los Angeles Chargers 482 Chargers
-122 -140 + N/A -125 + -140 + -160 + -134 + N/A -150 -134 + -155  
Washington Commanders 481 Commanders
+1.5 -115 +1 -110 + N/A +1.5 -122 + +0.5 -115 + N/A +1.5 -120 + N/A N/A +1.5 -125 + +3 -120  
Los Angeles Chargers 482 Chargers
-1.5 -105 -1 -110 + N/A -1.5 even + -0.5 -105 + N/A -1.5 -100 + N/A N/A -1.5 +102 + -3 even  
Washington Commanders 481 Commanders
o47.5 -112 o23 -110 + N/A o23.5 -105 + o23.5 -110 + N/A o23.5 -105 + o23.5 -115 + N/A o23.5 even + o48.5 -115  
Los Angeles Chargers 482 Chargers
u47.5 -108 u23 -110 + N/A u23.5 -115 + u23.5 -110 + N/A u23.5 -115 + u23.5 -115 + N/A u23.5 -122 + u48.5 -105  
Washington Commanders 481 Commanders
+102 +105 + N/A +114 + N/A N/A +112 + N/A N/A +108 + +130  
Los Angeles Chargers 482 Chargers
-122 -125 + N/A -135 + N/A N/A -130 + N/A N/A -136 + -155  
Washington Commanders 481 Commanders
+1.5 -115 N/A N/A +0.5 -118 + +0.5 -115 + N/A +1.5 -136 + +0.5 -130 + N/A N/A +3 -120  
Los Angeles Chargers 482 Chargers
-1.5 -105 N/A N/A -0.5 -102 + -0.5 -105 + N/A -1.5 +112 + -0.5 even + N/A N/A -3 even  
Washington Commanders 481 Commanders
o47.5 -112 o14 -115 + N/A o14.5 -105 + o13.5 -125 + N/A o14.5 -102 + o13.5 -125 + N/A N/A o48.5 -115  
Los Angeles Chargers 482 Chargers
u47.5 -108 u14 -105 + N/A u14.5 -115 + u13.5 +105 + N/A u14.5 -122 + u13.5 -105 + N/A N/A u48.5 -105  
Washington Commanders 481 Commanders
+102 +115 + N/A +114 + +110 + N/A +110 + N/A N/A N/A +130  
Los Angeles Chargers 482 Chargers
-122 -135 + N/A -135 + -130 + N/A -132 + N/A N/A N/A -155  
Washington Commanders 481 Commanders
+1.5 -115 N/A N/A +0.5 -142 + +0.5 -140 + N/A +1.5 -148 + +0.5 -150 + N/A N/A +3 -120  
Los Angeles Chargers 482 Chargers
-1.5 -105 N/A N/A -0.5 +120 + -0.5 +120 + N/A -1.5 +124 + -0.5 +115 + N/A N/A -3 even  
Washington Commanders 481 Commanders
o47.5 -112 o10 even + N/A o9.5 -135 + o9.5 -130 + N/A o9.5 -128 + o9.5 -130 + N/A N/A o48.5 -115  
Los Angeles Chargers 482 Chargers
u47.5 -108 u10 -120 + N/A u9.5 +114 + u9.5 +110 + N/A u9.5 +106 + u9.5 even + N/A N/A u48.5 -105  
Washington Commanders 481 Commanders
+102 +110 + N/A +105 + +105 + N/A +114 + N/A N/A N/A +130  
Los Angeles Chargers 482 Chargers
-122 -130 + N/A -122 + -125 + N/A -138 + N/A N/A N/A -155  
Washington Commanders 481 Commanders
+1.5 -115 +0.5 -135 + N/A +0.5 -125 + +0.5 -135 + N/A +1.5 -156 + +0.5 -120 + N/A N/A +3 -120  
Los Angeles Chargers 482 Chargers
-1.5 -105 -0.5 +115 + N/A -0.5 +105 + -0.5 +115 + N/A -1.5 +126 + -0.5 -110 + N/A N/A -3 even  
Washington Commanders 481 Commanders
o47.5 -112 o13.5 -110 + N/A o13.5 +102 + o13.5 -110 + N/A o13.5 +106 + o13.5 -110 + N/A N/A o48.5 -115  
Los Angeles Chargers 482 Chargers
u47.5 -108 u13.5 -110 + N/A u13.5 -122 + u13.5 -110 + N/A u13.5 -126 + u13.5 -120 + N/A N/A u48.5 -105  
Washington Commanders 481 Commanders
+102 even + N/A +105 + even + N/A -102 + N/A N/A N/A +130  
Los Angeles Chargers 482 Chargers
-122 -120 + N/A -125 + -125 + N/A -118 + N/A N/A N/A -155  

The Commanders will take on the Chargers in this week's NFL action. Kickoff is set for 4:25 p.m. EDT at SoFi Stadium in Inglewood, Calif. The game will be broadcast live on FOX. Here's everything you need to know about Commanders vs. Chargers odds, the latest NFL spreads, NFL over/unders and more.

The Chargers opened as a -2.5 point favorite over Commanders. The total is set at over/under 48 total points scored by both teams combined.

Be sure to check out the latest NFL Odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 10/5/25

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Washington Commanders vs. Los Angeles Chargers Best Bet

After a slow start to the season, Hampton has been a real bellcow back over the last 2 weeks with 31 carries and 12 targets in that time frame. He got nearly 90% of the snaps last week with Najee out for season and has been used heavily in the redzone this season with 10 carries thus far. Even in a tough matchup, the odds don't factor in Hamptons role nearly enough. I have the true odds here around -150 making this a great EV bet.

Washington Commanders vs. Los Angeles Chargers Best Bet: Omarion Hampton Touchdowns (-120)

(Pick via Grant Neiffer)


PLACE THIS BET INSTANTLY AT bet365!

Looking for more best bets? Check out our free NFL picks and our premium subscription for the best picks! Looking for line movements? Check out the latest Commanders vs. Chargers betting line movement.

What Time is the Washington Commanders vs. Los Angeles Chargers Game?

The Washington Commanders and Los Angeles Chargers play at 4:25 PM ET on Sunday, October 5th.

Where is the Washington Commanders vs. Los Angeles Chargers Game Being Played?

This game is going to be played at SoFi Stadium in Inglewood, CA.

How Can I Watch the Washington Commanders vs. Los Angeles Chargers?

You can watch Washington Commanders vs. Los Angeles Chargers on FOX.

Can The Commanders Beat The Chargers?

The Commanders are 2.5 point underdogs, but anything can happen in the NFL.

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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