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Featured Last Updated Oct 23 2025, 4:18 PM

NFL: Dallas Cowboys vs. Denver Broncos Prediction, Odds, Best Bet

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
8 minute read
NFL: Dallas Cowboys vs. Denver Broncos Prediction, Odds, Best Bet

Featured Image Credit: Kevin Jairaj-Imagn Images

DAL @ DEN Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Final
Dallas Cowboys 279 Cowboys
+4.5 -110 +2.5 +105 +2.5 even +2.5 -105 +2.5 -104 +2.5 -105 +2.5 -100 +4.5 -120 -2.5 -120 +2.5 -110 +3.5 -105  
Denver Broncos 280 Broncos
-4.5 -110 -2.5 -125 -2.5 -120 -2.5 -115 -2.5 -117 -2.5 -125 -2.5 -120 -4.5 even +2.5 -120 -2.5 -112 -3.5 -115  
Final
Dallas Cowboys 279 Cowboys
o45.5 -110 o26 -110 N/A o25.5 -110 o26.5 even N/A o26.5 -110 o26.5 -110 o28.5 -110 o26.5 -107 o51.5 -112  
Denver Broncos 280 Broncos
u45.5 -110 u26 -110 N/A u25.5 -110 u26.5 -124 N/A u26.5 -110 u26.5 -110 u28.5 -130 u26.5 -117 u51.5 -108  
Final
Dallas Cowboys 279 Cowboys
+164 +150 +145 +136 +135 +135 +138 N/A -170 +132 +160  
Denver Broncos 280 Broncos
-198 -180 -180 -166 -170 -180 -170 N/A +120 -165 -198  
Final
Dallas Cowboys 279 Cowboys
+4.5 -110 +0.5 -125 +0.5 -120 +0.5 -135 N/A +0.5 -135 +1.5 -148 +2.5 +105 -2.5 -170 +1.5 -148 +3.5 -105  
Denver Broncos 280 Broncos
-4.5 -110 -0.5 +105 -0.5 -105 -0.5 +114 N/A -0.5 +105 -1.5 +118 -2.5 -135 +2.5 +115 -1.5 +120 -3.5 -115  
Final
Dallas Cowboys 279 Cowboys
o45.5 -110 o9.5 -130 N/A o9.5 -125 N/A o9.5 -140 o9.5 -138 o9.5 -160 o10.5 -140 o9.5 -152 o51.5 -112  
Denver Broncos 280 Broncos
u45.5 -110 u9.5 +110 N/A u9.5 +105 N/A u9.5 +110 u9.5 +112 u9.5 +120 u10.5 -105 u9.5 +123 u51.5 -108  
Final
Dallas Cowboys 279 Cowboys
+164 +120 +140 +120 N/A +115 +116 N/A -400 +120 +160  
Denver Broncos 280 Broncos
-198 -140 -180 -142 N/A -145 -140 N/A +260 -150 -198  
Final
Dallas Cowboys 279 Cowboys
+4.5 -110 +2.5 -110 N/A +1.5 -105 N/A N/A +2.5 -110 N/A +1.5 -140 +1.5 -110 +3.5 -105  
Denver Broncos 280 Broncos
-4.5 -110 -2.5 -110 N/A -1.5 -115 N/A N/A -2.5 -110 N/A -1.5 -105 -1.5 -113 -3.5 -115  
Final
Dallas Cowboys 279 Cowboys
o45.5 -110 o26 -110 N/A o26.5 -105 N/A N/A o25.5 -110 o25.5 -115 o24.5 -130 o25.5 -109 o51.5 -112  
Denver Broncos 280 Broncos
u45.5 -110 u26 -110 N/A u26.5 -115 N/A N/A u25.5 -110 u25.5 -115 u24.5 -110 u25.5 -114 u51.5 -108  
Final
Dallas Cowboys 279 Cowboys
+164 +120 N/A +130 N/A N/A +136 N/A even +123 +160  
Denver Broncos 280 Broncos
-198 -140 N/A -155 N/A N/A -156 N/A -140 -152 -198  
Final
Dallas Cowboys 279 Cowboys
+4.5 -110 N/A N/A +0.5 -105 N/A N/A +1.5 -114 +1.5 -115 +1.5 -130 N/A +3.5 -105  
Denver Broncos 280 Broncos
-4.5 -110 N/A N/A -0.5 -115 N/A N/A -1.5 -108 -1.5 -115 -1.5 -110 N/A -3.5 -115  
Final
Dallas Cowboys 279 Cowboys
o45.5 -110 o15.5 -110 N/A o15.5 -115 N/A N/A o19.5 -138 o16.5 -105 o16.5 -110 N/A o51.5 -112  
Denver Broncos 280 Broncos
u45.5 -110 u15.5 -110 N/A u15.5 -105 N/A N/A u19.5 +106 u16.5 -125 u16.5 -130 N/A u51.5 -108  
Final
Dallas Cowboys 279 Cowboys
+164 +140 N/A +124 N/A N/A +132 N/A +110 N/A +160  
Denver Broncos 280 Broncos
-198 -160 N/A -148 N/A N/A -162 N/A -170 N/A -198  
Final
Dallas Cowboys 279 Cowboys
+4.5 -110 N/A N/A +0.5 -122 N/A N/A +1.5 -130 -0.5 +125 -0.5 +110 N/A +3.5 -105  
Denver Broncos 280 Broncos
-4.5 -110 N/A N/A -0.5 +102 N/A N/A -1.5 +108 +0.5 -165 +0.5 -165 N/A -3.5 -115  
Final
Dallas Cowboys 279 Cowboys
o45.5 -110 o10 -115 N/A o10.5 +110 N/A N/A o10.5 +460 o10.5 +110 o10.5 +105 N/A o51.5 -112  
Denver Broncos 280 Broncos
u45.5 -110 u10 -105 N/A u10.5 -130 N/A N/A u10.5 -800 u10.5 -140 u10.5 -155 N/A u51.5 -108  
Final
Dallas Cowboys 279 Cowboys
+164 +125 N/A +124 N/A N/A +130 N/A -125 N/A +160  
Denver Broncos 280 Broncos
-198 -150 N/A -148 N/A N/A -160 N/A -115 N/A -198  
Final
Dallas Cowboys 279 Cowboys
+4.5 -110 +0.5 -125 N/A +0.5 -115 N/A N/A +1.5 -138 N/A +1.5 -140 N/A +3.5 -105  
Denver Broncos 280 Broncos
-4.5 -110 -0.5 +105 N/A -0.5 -105 N/A N/A -1.5 +114 N/A -1.5 -105 N/A -3.5 -115  
Final
Dallas Cowboys 279 Cowboys
o45.5 -110 o14.5 even N/A o14.5 -102 N/A N/A o14.5 +108 o14.5 even o14.5 -105 N/A o51.5 -112  
Denver Broncos 280 Broncos
u45.5 -110 u14.5 -120 N/A u14.5 -118 N/A N/A u14.5 -128 u14.5 -130 u14.5 -140 N/A u51.5 -108  
Final
Dallas Cowboys 279 Cowboys
+164 +110 N/A +114 N/A N/A +112 N/A +125 N/A +160  
Denver Broncos 280 Broncos
-198 -130 N/A -135 N/A N/A -140 N/A -175 N/A -198  

The Cowboys will take on the Broncos in this week's NFL action. Kickoff is set for 4:25 p.m. EDT at Empower Field at Mile High in Denver, Colo. The game will be broadcast live on CBS. Here's everything you need to know about Cowboys vs. Broncos odds, the latest NFL spreads, NFL over/unders and more.

The Broncos opened as a -3.5 point favorite over Cowboys. The total is set at over/under 50.5 total points scored by both teams combined.

Be sure to check out the latest NFL odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 10/27/25

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Dallas Cowboys vs. Denver Broncos Best Bet

Dak Prescott continue to put on MVP performance after MVP performance. Dak when he is healthy is one of the best quarterbacks in the NFL. Bo Nix, on the other hand is experiencing a bit of a sophomore slump. While their record is impressive, Nix's PFF grade is 66.1, a rough mark for the second year quarterback.

While the Cowboy's defense is lacking, I am confident that their offense is potent and explosive enough to keep them in games. Dak's big time throw rate is one of the highest in the league, coming in at 5.76%. The Cowboys will score enough to keep them in this game.

Dallas Cowboys vs. Denver Broncos Best Bet: Dallas Cowboys +3.5 (-115)

(Pick from Dylan Wilkerson)


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What Time is the Dallas Cowboys vs. Denver Broncos Game?

The Dallas Cowboys vs. Denver Broncos game is at 4:25 PM ET on Sunday, October 26th.

Where is the Dallas Cowboys vs. Denver Broncos Game Being Played?

This game will be played at Empower Field in Denver, CO.

How Can I Watch Dallas Cowboys vs. Denver Broncos?

You can watch Dallas Cowboys vs. Denver Broncos on CBS.

Can the Cowboys Beat the Broncos?

Of course! The Cowboys are only a 3.5 point underdog so anyone can win.

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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