NFL Odds Divisional Playoff Round: Packers vs 49ers Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

6 minute read

Here's everything you need to know about the NFL odds for Divisional Playoff Round: Packers vs 49ers lines, spreads, betting trends and more.

The second round of the NFL Playoffs continues with what has the makings of a lopsided NFC clash between the Green Bay Packers and San Francisco 49ers. The betting odds see Green Bay as a double-digit underdog after stunning the Cowboys in Dallas last week. Coverage begins from Levi's Stadium in Santa Clara on Saturday, January 20 at 8:15 p.m. ET on FOX.

Make sure to check out our Super Bowl 58 odds page before the final game of the season is here!

Green Bay Packers vs San Francisco 49ers Odds

• Opening point spread: 49ers -9.5
• Opening moneyline: 49ers -500/Packers +400
• Opening total: Over/Under 48.5 points scored
• Time: 8:15 p.m. ET Saturday (FOX)

UPDATE 7 P.M. ET SATURDAY: With kickoff 75 minutes out, the 49ers are laying 10 points in BetMGM's Divisional Round odds market. San Francisco opened -9.5 late Sunday night and went to -10 shortly thereafter.

On Monday, the line dipped to San Fran -9.5 (-120), and the number bottomed out at -9 briefly on Tuesday. It spent the past few days at Niners -9.5 at various juice (flat/-115/-120), then went to -10 this afternoon.

It's two-way spread play, with 53% of bets on the Packers/59% of money on the Niners. However, it's heavy Green Bay action on the moneyline, at 83% of bets/73% of money. The Packers are currently +375.

"We're hoping for a 49ers win and a Packers cover here," BetMGM's Christian Cipollini said.

BetMGM's total opened at 49.5, then spent pretty much all week at 50.5. The Over is taking 69% of bets/70% of dollars.

The player prop taking the most tickets is Packers running back Aaron Jones Anytime Touchdown, currently even money. Christian McCaffrey First TD Scorer is taking the second-most tickets among all player props. The Niners running back is +275 in the First TD market.

UPDATE 2 P.M. ET THURSDAY: San Fran went from -9.5 to -10 and back to -9.5 at TwinSpires Sportsbook. Green Bay is landing 60% of early spread tickets/58% of early spread money.

"Another trendy 'dog this weekend. The Packers are attracting a majority of the support so far," Lucas said, while noting the book is rooting against a Saturday night outright upset, too. "Packers moneyline would be a big blow, as we're seeing 3/1 tickets and 9/1 money on Green Bay to win outright."

The total opened and remains 50.5 at TwinSpires, with 61% of tickets/58% of dollars on the Over.

UPDATE 2 P.M. ET THURSDAY: San Fran went from -9.5 to -10 and back to -9.5 at TwinSpires Sportsbook. Green Bay is landing 60% of early spread tickets/58% of early spread money.

"Another trendy 'dog this weekend. The Packers are attracting a majority of the support so far," Lucas said, while noting the book is rooting against a Saturday night outright upset, too. "Packers moneyline would be a big blow, as we're seeing 3/1 tickets and 9/1 money on Green Bay to win outright."

The total opened and remains 50.5 at TwinSpires, with 61% of tickets/58% of dollars on the Over.

UPDATE 9:30 P.M. ET SUNDAY: Green Bay (10-8 SU and ATS) pulled a super shocker on Super Wild Card Weekend. The Packers closed as 7-point road underdogs at Dallas, but built a 27-0 first-half lead and rolled to a 48-32 victory.

That 16-point final margin was definitely deceptive. No. 7 seed Green Bay led 48-16 with 10 minutes remaining. No. 2 seed Dallas got a couple window-dressing TDs in the final six minutes.

The Packers are on a 7-2 SU/6-3 ATS stretch, including 4-0 SU/3-1 ATS in their last four outings.

Meanwhile, No. 1 seed San Francisco (12-5 SU/9-8 ATS) rested up with a bye week. The 49ers lost their regular-season finale against the L.A. Rams 21-20 as 4.5-point home favorites. But the Niners rested many starters, having already clinched the No. 1 seed.

Prior to that setback, San Fran rode a 7-1 SU spree to the top seed. So The SuperBook wasted no time tonight in opening at San Francisco -9.5.

"Obviously, the Packers looked awesome today. But San Francisco's power rating is in a different class, and we're expecting the public to still be on the Niners," SuperBook risk supervisor Chase Michaelson said. "We'd like to keep the spread above the teaser line (-8.5) if possible."

While the spread is stable tonight, the total is already on the move. The SuperBook jumped from 48.5 to 49.5/50.5 in its NFL odds Divisional Playoff Round market.

"San Francisco's defense is so good that we shaded the total Under a little bit," Michaelson said. "But we took some Over money, so we're up to 50.5."

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Divisional Playoff Round Report containing spreads, lines, and trends for every NFL matchup.

Packers vs 49ers Pick, Prediction

Action Network NFL betting expert Brandon Anderson offers this prediction:

I didn't bet the Packers against the Cowboys but had this matchup circled if Green Bay survived. This red-hot Packers offense can score on the Niners. Green Bay should be able to run the ball against a beatable run defense, and Love has played like an MVP candidate and can be the best player on the field in this game. The Packers' offense can hang or cover through the back door.

But what if they do even more? San Francisco's defense is worse at home and worse in the first half, leaving the door open for the Packers to hang around. The Niners haven't been tested often, and they haven't really played a meaningful game since getting shellacked on Christmas night by the Ravens when Brock Purdy turned into a pumpkin.

What happens if Purdy sails another couple of early throws after a month of rust? Will his confidence fade? Will Kyle Shanahan's? This Niners offense should demolish this bad Packers D, but if San Francisco doesn't slam the door early, the pressure is all on the 49ers. Green Bay can win in the trenches, control the clock with Aaron Jones and long drives keeping all those Niners weapons on the sidelines and let Love cook against a vulnerable secondary.

Matt LaFleur is 20-9 ATS (69%) as an underdog, and his aggression will give Green Bay an advantage in this game against Shanahan. The Packers are 17-12 straight up as dogs under LaFleur, giving bettors an awesome 50% ROI on the moneyline, the best for any active coach. Road teams that missed last year's playoffs are 27-13 ATS (68%) in the Divisional Round. These are young, rising teams that just proved themselves with a big win, like the Packers.

Every bettor's instinct is to smash the rested, juggernaut 1-seeds in the Divisional Round, but history says to do the exact opposite. Home teams are just 42% ATS this round over the last two decades, and 1-seeds are even worse at 35%, including an awful 10-25-1 ATS (29%) when favored by 10 or fewer points. Only twice in the last two decades have both 1-seeds covered and won; they've gone 0-2 ATS a whopping eight times.

Home teams this round on a one-game losing streak — maybe because they rested and lost Week 18 like the 49ers and are rusty three weeks later? — are an ugly 3-15 ATS, with just one of the 18 winning by double digits.

I'm riding with the trends, and I'm riding with Love and LaFleur. Give me Packers +9.5

Pick: Packers +9.5 (-110)

For more NFL picks, check out Action Network's NFL Divisional Round Playoffs: How to Bet Every Game & Every Team.

The One Stat to Know About Packers vs 49ers

Action Network NFL researcher Evan Abrams offers his top betting stat:

The Packers are 7-6-1 SU as underdogs this season. That is one win away from tying the record for most straight up underdog wins in a single season in the Super Bowl era, including the playoffs.

For more NFL betting stats, check out Action Network's NFL Divisional Round Playoffs Betting Trends, Stats, Notes.

ESPN BET Sportsbook is almost here - use our promo code to join and claim your bonus offer!

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson