NFL Odds Week 1: Cardinals vs Commanders Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

2 minute read

The first Sunday of the 2023 NFL season is upon us, and that means it's time for NFL odds for Week 1: Cardinals vs Commanders lines, spreads and betting trends.

The Cardinals and Commanders meet at FedExField in Landover on Sunday, September 10 at 1:00 p.m. ET on FOX.

Here's everything you need to know about the NFL odds for the Week 1 game between the Cardinals and Commanders: the opening lines, spreads, betting trends and more. Check back regularly for updates.

Arizona Cardinals vs Washington Commanders Odds

• Opening point spread: Commanders -6
• Opening moneyline: Commanders -310/Cardinals +250
• Opening total: Over/Under 39.5 points scored
• Time: 1 p.m. ET Sunday, Sept. 10 (FOX)

UPDATE 10:30 A.M. ET SUNDAY: Nobody wants much to do with the Cardinals at BetMGM Nevada. The Commanders opened -6, initially receded to -5.5, but they've been at -7 for almost three weeks.

"I can't believe the Commanders are favored by 7 over any professional team," BetMGM Nevada's Scott Shelton said. "But all the tickets and all the money are on the Commanders. Tickets are 6/1 and almost all the money is on Washington. The public is all over Washington."

That includes a $200,000 bet on Commanders -7. Now, you're probably not looking to get that much down -- but if you are betting Cardinals vs Commanders, don't forget to check out our bet365 bonus code!

UPDATE 5:30 P.M. ET WEDNESDAY: The Commanders hit BetMGM's NFL Week 1 odds board as 5.5-point favorites, and they've been at -7 since Aug. 22. Arizona has plenty of issues, not the least of which is Kyler Murray (ACL) missing at least the first four weeks.

Early spread tickets are 6/1 and early spread money 9/1-plus in favor of Washington.

Thanks in part to Arizona's lackluster situation at QB, the total is the lowest on the NFL odds Week 1 board. BetMGM opened the total at 41.5 and is down to 38. Tickets and money are in the 2/1 range on the Under.

Last week, the Cards released Colt McCoy – who was expected to start in Murray's absence – and named Josh Dobbs the starter. Dobbs has only been with Arizona since Aug. 24, acquired by the Cards in a trade with Cleveland.

UPDATE 1:30 P.M. ET MONDAY, AUG. 28: Washington is looking to move forward under new ownership, with the Dan Snyder era over. The Commanders were a perfectly middling 8-8-1 SU and ATS last season. Washington had a reasonable chance to make the playoffs before a three-game SU and ATS skid from Weeks 15-17.

Arizona is just hoping for the return of QB Kyler Murray, who tore his right ACL late last season. Murray hasn't practiced yet, and there's no set timetable for his return. Last year, the Cards limped to a 4-13 SU mark (8-9 ATS).

On Aug. 24, The SuperBook moved the Commanders from -6 to -7. The total moved from 39.5 to 40 shortly after opening in May. But the number dipped to 38.5 on Aug. 14. While The SuperBook's spread/total opened back on May 11, the moneyline just opened today, hence no movement so far.

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• Compare the latest NFL Odds from the best sportsbooks before placing a bet on this week's games.
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Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson