NFL Odds Week 12: Bills vs Eagles Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

4 minute read

Week 12 of the NFL season continues with a heavyweight non-conference clash between the Buffalo Bills and Philadelphia Eagles. The betting odds see Philly as a short home favorite as they try to build upon their lead in the conference. Coverage begins from Lincoln Financial Field in South Philly on Sunday, November 26 at 1:00 p.m. ET on CBS.

Here's everything you need to know about the NFL odds for Week 12: Bills vs Eagles lines, spreads, betting trends and more.

ESPN BET Sportsbook is here! Use our promo code to join and claim your bonus offer!

Buffalo Bills vs Philadelphia Eagles Odds

• Opening point spread: Eagles -3 (-120)
• Opening moneyline: Eagles -180/Bills +150
• Opening total: Over/Under 47.5 points scored
• Time: 4:25 p.m. ET Sunday (CBS)

UPDATE 10 A.M. ET SUNDAY: BetMGM has Philadelphia at -3 (-105) in its NFL odds Week 12 market on game day. The Eagles opened -3 (-120) and spent the first half of the week mostly at -3.5, at various juice.

Philly went to -3 (-115) Thursday, -3 flat Friday and -3 (-105) this morning. Spread tickets and money are running 2/1 Eagles. Moneyline action is leaning toward Philadelphia, as well, at 57% of tickets/64% of cash.

The total went from 47.5 to 48.5 Tuesday, then this morning inched up to 49. The Over is taking 59% of tickets/61% of money.

UPDATE 4 P.M. ET WEDNESDAY: Philly, coming off its big win at Kansas City, moved from -3 to -3.5 at TwinSpires Sportsbook. Early ticket count is 2/1 and early money 3/1 on the Eagles.

"It's a mix of sharp and public play on the Eagles so far," Lucas said. "The Eagles are off a prime-time win, so we expect them to take a lot of money. We'll definitely need the Bills."

The total nudged up from 48 to 48.5, with tickets and money in the 2/1 range on the Over.

UPDATE 10:30 P.M. ET TUESDAY: The Eagles (9-1 SU/6-2-2 ATS) rallied from a 17-7 halftime deficit to beat the Chiefs in the Week 11 Monday nighter. Philly shut out K.C. in the second half, winning 21-17 as a 2.5-point road underdog.

On Sunday night, The SuperBook opened Bills-Eagles at Philadelphia -3 (-120), then moved to 3.5 (even) Monday morning. This morning, even after the Eagles' big road win, the line actually receded to -3 (-120) again.

However, the Bills-Eagles total is up a point, going from 47.5 to 48 Monday afternoon, then to 48.5 this morning.

UPDATE 10 P.M. ET SUNDAY: Philadelphia (8-1 SU/5-2-2 ATS) is on a modest 3-0 SU/2-0-1 ATS upswing. But the Eagles still have to finish out Week 11 before focusing on Buffalo. Philly meets Kansas City on Monday night in a Super Bowl rematch.

Buffalo (6-5 SU/4-7 ATS) hopes its derailed season is back on the tracks after a Week 11 rout. The Bills pounded the Jets 32-6 giving 8.5 points at home, ending a 2-4 SU/0-6 ATS slide.

The SuperBook opened Bills-Eagles at Philly -3 (-120) on its NFL Week 12 odds board.

"This line will change depending on what the Eagles do Monday night in Kansas City," Michaelson said. "But we felt opening anything higher than 3 is really asking for wiseguy action on Buffalo, particularly with Philly on a short week and emotional comedown from whatever the result is in a Super Bowl rematch."

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Week 12 Report containing spreads, lines, and trends for every NFL matchup.

Bills vs Eagles Pick, Prediction

Action Network NFL betting expert Brandon Anderson offers this prediction:

Check back soon for picks!

Pick: TBD

For more NFL picks, check out Action Network's NFL Week 12: How to Bet Every Game & Every Team.

The One Stat to Know About Bills vs Eagles

Action Network NFL researcher Evan Abrams offers his top betting stat:

Check back soon for betting stats!

For more NFL betting stats, check out Action Network's NFL Week 12 Betting Trends, Stats, Notes.

ESPN BET Sportsbook is almost here - use our promo code to join and claim your bonus offer!

Where to place a bet this NFL Season?

• Use our exclusive BetMGM Bonus Code VIBONUS1600 to unlock BetMGM's welcome offer for new sportsbook users!
• Compare the latest NFL Odds from the best sportsbooks before placing a bet on this week's games.
• Sports betting is live in North Carolina! Check out our list of North Carolina Sportsbooks and get ready for the NFL season.
• Our DraftKings Promo Code earns users $150 in bonus bets when you bet $5. Sign up today!

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson