NFL Odds Week 15: Lines, Spreads, Betting Trends For All 16 Games

Patrick Everson Sports Betting Expert

14 minute read

2024 NFL Odds Week 15

NFL odds for Week 15 bring with them the end of the bye weeks. So all 32 teams are in action every week, the rest of the way.

The marquee matchup in odds for NFL Week 15: Buffalo Bills vs. Detroit Lions, in what could be a Super Bowl preview. Another key contest: Pittsburgh Steelers vs. Philadelphia Eagles.

Here’s everything you need to know about the NFL odds Week 15 market: opening lines, spreads and betting trends for every game, as multiple oddsmakers provide insights on Week 15 NFL odds and action. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

NFL Odds for Every Game of NFL Week 15

Los Angeles Rams vs. San Francisco 49ers Odds

• Opening point spread: 49ers -2.5
• Opening moneyline: 49ers TBA/Rams TBA
• Opening total: Over/Under 47.5 points scored
• Time: 8:15 p.m. ET Thursday (Prime)

UPDATE 10:30 P.M. ET SUNDAY: Los Angeles (7-6 SU/6-7 ATS) played the barnburner of the week and stayed in the NFC West hunt in the process. The Rams, catching 3.5 points at home, outlasted red-hot Buffalo 44-42. L.A. is 6-2 SU in its last eight games.

San Francisco (6-7 SU/5-8 ATS) overcame the absence of Christian McCaffrey while ending a three-game SU and ATS slide. The 49ers rolled over Chicago 38-13 laying 3 points at home.

The Rams-Niners line was on the move early tonight in The SuperBook's NFL odds Week 15 market.

"We opened 49ers -2.5 and got bet down to 49ers -1.5 pretty quickly," SuperBook executive director John Murray said. "Great win for the Rams today, and now they have to turn around and go on the road on a short week.

"Today really showed what the Rams' offense is capable of when healthy. Their wide receivers are great."

Puca Nakua had 12 receptions for 162 yards and what proved to be the game-winning touchdown. Cooper Kupp had five catches for 85 yards and a TD.

The total is also on the move tonight, climbing from 47.5 to 48/48.5.

Kansas City Chiefs vs. Cleveland Browns Odds

• Opening point spread: Chiefs -6
• Opening moneyline: Chiefs TBA/Browns TBA
• Opening total: Over/Under 44.5 points scored
• Time: 1 p.m. ET Sunday (CBS)

UPDATE 11:30 P.M. ET SUNDAY: Kansas City (12-1 SU/5-8 ATS) just doesn't lose one-score games. No matter what. In the Week 14 Sunday nighter, the Chiefs edged the L.A. Chargers 19-17 on a Matthew Wright 31-yard field goal that was good after doinking off the upright.

K.C. has won its last 15 one-score games, including 10 such contests this season. What the Chiefs aren't doing, though, is covering, as they're now on an 0-7 ATS nosedive.

Cleveland (3-10 SU/4-9 ATS) saw its difficult season continue in Week 14. The Browns lost to Pittsburgh 27-14 catching 6 points on the road. Jameis Winston & Co. are 1-4 SU and ATS in their last five games.

The SuperBook opened Chiefs-Browns at Kansas City -6 in Week 15 NFL odds. The game was taken off the board once Chargers-Chiefs kicked off Sunday night. Chiefs-Browns will go back up Monday morning.

"Patrick Mahomes vs. Jameis Winston. That’s a pretty fun QB matchup. We’ll need Cleveland," SuperBook executive director John Murray said.

Miami Dolphins vs. Houston Texans Odds

• Opening point spread: Texans -2
• Opening moneyline: Texans TBA/Dolphins TBA
• Opening total: Over/Under 47 points scored
• Time: 1 p.m. ET Sunday (CBS)

UPDATE 10:30 P.M. ET SUNDAY: Houston (8-5 SU/5-8 ATS) is coming off its bye week. In Week 13, the Texans blew a 23-6 fourth-quarter lead at Jacksonville, but held on for a 23-20 victory. Houston failed to cover as 3.5-point chalk.

Miami (6-7 SU and ATS) got all it could handle as a 6.5-point favorite vs. the New York Jets. The Dolphins needed a field goal in the final seconds to tie it at 26. Miami then won 32-26 in overtime.

Texans-Dolphins opened at Houston -2 tonight, with no movement so far at The SuperBook.

Baltimore Ravens vs. New York Giants Odds

• Opening point spread: Ravens -14
• Opening moneyline: Ravens TBA/Giants TBA
• Opening total: Over/Under 43.5 points scored
• Time: 1 p.m. ET Sunday (CBS)

UPDATE 10:30 P.M. ET SUNDAY: Baltimore (8-5 SU/6-6-1 ATS) got a timely bye in Week 14, after losing two of its last three games. In Week 13, the Ravens closed as 3-point home favorites vs. Philadelphia and got out to an early 9-0 lead. But Baltimore ultimately lost 24-19.

New York (4-9 SU/6-7 ATS) was on the brink of taking New Orleans to overtime. But Graham Gano's 35-yard field-goal attempt in the waning seconds was blocked, and the Giants lost 14-11 getting 5.5 points at home.

Baltimore opened -14 tonight in The SuperBook's NFL Week 14 odds. After a couple hours, the number climbed to Ravens -14.5.

Dallas Cowboys vs. Carolina Panthers Odds

• Opening point spread: Pick
• Opening moneyline: Cowboys TBA/Panthers TBA
• Opening total: Over/Under 43 points scored
• Time: 1 p.m. ET Sunday (FOX)

UPDATE 1 A.M. ET TUESDAY: Dallas (5-8 SU and ATS) lost in inexplicable fashion in the Week 14 Monday night game vs. Cincinnati. Tied at 20 with two minutes left, the Cowboys forced the Bengals to punt on fourth-and-27 from Cincy's 29.

Then the Cowboys partially blocked the punt. But Amani Oruwariye tried to field the punt at Cincinnati's 42 and muffed it, and the Bengals recovered. Three plays later, Dallas gave up a 40-yard TD pass to Ja'Marr Chase and went on to lose 27-20 as 4.5-point home 'dogs.

That ended a modest two-game SU and ATS upswing for Dallas and likely killed any playoff hopes.

Cowboys-Panthers opened Carolina -1 at DraftKings on Sunday night, and the line remains there now. The Panthers are landing 61% of early spread tickets/95% of early spread dollars.

The total opened and remains 43.5, with tickets and money just shy of 2/1 on the Over.

UPDATE 10:30 P.M. ET SUNDAY: Carolina (3-10 SU/6-7 ATS) nearly pulled off one of the bigger upsets of the season. The Panthers were 14-point pups at Philadelphia and led 16-14 entering the fourth quarter.

But Bryce Young & Co. ultimately fell 22-16 when their final drive came up short. Xavier Legette had a potential go-ahead touchdown catch within his grasp with 52 seconds left, but couldn't hang on.

Dallas (5-7 SU and ATS) still has Week 14 work to do, hosting Cincinnati on Monday night.

The SuperBook opened Cowboys-Panthers at pick 'em in the NFL odds Week 15 market. And the first move tonight came about two hours later, to Carolina -1.

Washington Commanders vs. New Orleans Saints Odds

• Opening point spread: Commanders -7
• Opening moneyline: Commanders TBA/Saints TBA
• Opening total: Over/Under 43.5 points scored
• Time: 1 p.m. ET Sunday (FOX)

UPDATE 10:30 P.M. ET SUNDAY: Washington (8-5 SU/8-4-1 ATS) is coming off its bye and hoping to make a playoff push. In Week 13, the Commanders halted a three-game SU and ATS skid by routing Tennessee 42-19 as 6-point home faves.

New Orleans (5-8 SU and ATS) didn't look great in Week 14, but was effective enough. The Saints held on for a 14-11 win over the New York Giants, but failed to cover as 5.5-point road favorites. New Orleans clinched it by blocking a field-goal attempt in the waning seconds.

However, Saints QB Derek Carr suffered an injured left hand and possible concussion late in the game. That prompted The SuperBook to open the Commanders -7 tonight, after having this game at Washington -3.5 on last week's lookahead line.

The spread is stable, and the total inched from 43.5 to 43.

Cincinnati Bengals vs. Tennessee Titans Odds

• Opening point spread: Bengals -5.5
• Opening moneyline: Bengals TBA/Titans TBA
• Opening total: Over/Under 48.5 points scored
• Time: 1 p.m. ET Sunday (FOX)

UPDATE 1 A.M. ET TUESDAY: Cincinnati (5-8 SU/7-6 ATS) got some good fortune in the Week 14 Monday nighter at Dallas. With two minutes left and the game tied at 20, the Bengals had to punt on fourth-and-27 from their own 29.

The punt was partially blocked and only traveled 13 yards. But the Cowboys' Amani Oruwariye then tried to field the ball on bounce and muffed it, and the Bengals recovered to get possession again.

Three plays later, Joe Burrow hit Ja'Marr Chase on a 40-yard touchdown pass, giving Cincy a 27-20 win and cover as 4.5-point road chalk.

DraftKings Sportsbook opened Bengals-Titans at Cincinnati -5.5 Sunday evening, went to -5 Monday morning and -4.5 after the Bengals-Cowboys game. The Bengals are taking 87% of early spread bets and money.

DK's total is down to 47.5 from a 48.5 opener in the NFL odds Week 15 market. The Under is seeing 54% of bets/84% of cash early on.

UPDATE 10:30 P.M. ET SUNDAY: Tennessee (3-10 SU/2-11 ATS) laid a Week 14 egg against a Jacksonville squad that doesn't have Trevor Lawrence. In a rock fight of a game, the Titans led 6-0 through three quarters. But Tennessee lost 10-6 giving 3 points at home.

Cincinnati (4-8 SU/6-6 ATS) isn't yet out of Week 14, traveling to Dallas for the Monday night game.

The Bengals opened -5.5 vs. the Titans in The SuperBook's Week 15 NFL odds. Cincy dipped to -5 tonight, while the total fell from 48.5 to 47.5.

New York Jets vs. Jacksonville Jaguars Odds

• Opening point spread: Jets -3
• Opening moneyline: Jets TBA/Jaguars TBA
• Opening total: Over/Under 40 points scored
• Time: 1 p.m. ET Sunday (FOX)

UPDATE 10:30 P.M. ET SUNDAY: New York (3-10 SU/4-9 ATS) got a field goal with 52 seconds left to take a 26-23 lead over Miami. But the Jets allowed a tying field goal in the final seconds. New York then lost 32-26 in overtime, while covering as a 6.5-point 'dog.

Jacksonville (3-10 SU/8-5 ATS) generated nothing through three quarters and trailed Tennessee 6-0. But the Jags did the rest of the scoring and won 10-6 as 3-point road pups.

Jets-Jags opened at New York -3 on The SuperBook's NFL Week 15 odds board, with no movement tonight.

Buffalo Bills vs. Detroit Lions Odds

• Opening point spread: Lions -3
• Opening moneyline: Lions TBA/Bills TBA
• Opening total: Over/Under 52.5 points scored
• Time: 4:25 p.m. ET Sunday (CBS)

UPDATE 11 P.M. ET SUNDAY: Detroit (12-1 SU/9-3-1 ATS) survived a Thursday night shootout against Green Bay in Week 14. The Lions won 34-31 on a final-seconds field goal, pushing as 3-point favorites.

It was the second straight game that Detroit didn't cover. Still, the Lions are 34-9 SU/32-10-1 ATS in their last 43 outings.

Buffalo (10-3 SU/8-5 ATS) saw its 7-0 SU/6-1 ATS spree come to end in Week 14. The Bills were 3.5-point road favorites vs. the L.A. Rams and fell just short in a 44-42 screamer.

The SuperBook opened Bills-Lions at Detroit -3 in the NFL odds Week 15 market tonight.

"We’ve already been bet down to Lions -2.5," SuperBook executive director John Murray said. "This looks like the best game of the week and one of the best of the year. Josh Allen should be the league MVP, and he gets to go against a Detroit defense that is very banged up.

"It will be interesting to see how Lions coach Dan Campbell handles any fourth-down decisions."

Pittsburgh Steelers vs. Philadelphia Eagles Odds

• Opening point spread: Eagles -4.5
• Opening moneyline: Eagles TBA/Steelers TBA
• Opening total: Over/Under 45.5 points scored
• Time: 4:25 p.m. ET Sunday (FOX)

UPDATE 11 P.M. ET SUNDAY: Philadelphia (11-2 SU/8-5 ATS) got way more than it expected from league doormat Carolina in Week 14. The Eagles trailed 16-14 entering the fourth quarter and barely held on for a 22-16 victory as 14-point home favorites.

Still, Philly stretched its winning streak to nine games (6-3 ATS).

Pittsburgh (10-3 SU and ATS) continues to impress both on the field and at the betting window. In Week 14, the Steelers beat Cleveland 27-14 giving 6 points at home.

Russell Wilson & Co. are 7-1 SU and ATS in their last eight games.

The Eagles opened -4.5 in The SuperBook's Week 15 NFL odds. There's been no movement tonight on the spread, but the total made three moves, from 45.5 to 45/44.5/44.

"The Eagles are on a roll right now, but the Steelers prove their doubters wrong just about every week," SuperBook executive director John Murray said. "This should be a good two-way action game. I wish it was in the early window, instead of the same time slot as Bills vs. Lions."

Indianapolis Colts vs. Denver Broncos Odds

• Opening point spread: Broncos -4.5
• Opening moneyline: Broncos TBA/Colts TBA
• Opening total: Over/Under 43 points scored
• Time: 4:25 p.m. ET Sunday (CBS)

UPDATE 10:30 P.M. ET SUNDAY: Denver (8-5 SU) is coming off its bye week during a surprising season. In Week 13, the Broncos outlasted Cleveland 41-32 laying 6.5 points at home, cashing for the fourth straight week.

In fact, Denver is 6-1 ATS in its last seven games (5-2 SU) and has the NFL's best overall spread-covering mark at 10-3 ATS.

Indianapolis (6-7 SU/8-5 ATS) is also coming off its bye. In Week 13, the Colts got a touchdown in the waning seconds to beat New England 25-24. But Indy failed to cover as 2.5-point road favorites.

Colts-Broncos opened at Denver -4.5 in The SuperBook's NFL Week 15 odds. The Broncos are now up to -5.

Tampa Bay Buccaneers vs. Los Angeles Chargers Odds

• Opening point spread: Chargers -3
• Opening moneyline: Chargers TBA/Buccaneers TBA
• Opening total: Over/Under 46.5 points scored
• Time: 4:25 p.m. ET Sunday (FOX)

UPDATE 11:30 P.M. ET SUNDAY: Los Angeles (8-5 SU/9-4 ATS) fell victim to the continuing good luck machine that is the Kansas City Chiefs. The Chargers lost 19-17 when K.C. banked in a 31-yard field goal as time expired.

L.A. covered as a 4.5-point road 'dog, moving to 6-1 ATS in its last seven games.

Tampa Bay (7-6 SU/8-5 ATS) has won three in a row SU and is 4-1 ATS in its last five games. In Week 14, the Bucs dispatched Las Vegas 28-13 laying 6.5 points at home.

Bucs-Chargers opened -3 tonight at The SuperBook, and the game came off the board once Chargers-Chiefs kicked off. Bucs-Chargers will go back up Monday morning.

New England Patriots vs. Arizona Cardinals Odds

• Opening point spread: Cardinals -6.5
• Opening moneyline: Cardinals TBA/Patriots TBA
• Opening total: Over/Under 45 points scored
• Time: 4:25 p.m. ET Sunday (CBS)

UPDATE 11 P.M. ET SUNDAY: Arizona (6-7 SU/8-5 ATS) is on an ill-timed three-game skid in a tight NFC West race. The Cardinals were 3-point home favorites vs. Seattle and lost 30-18.

New England (3-10 SU/5-7-1 ATS) got a much-needed bye in Week 14, after losing its last three games. In Week 13, the Patriots gave up a touchdown in the waning seconds, losing to Indianapolis 25-24. But the Pats covered as 2.5-point home 'dogs.

The SuperBook opened Arizona -6.5, with no movement tonight.

Green Bay Packers vs. Seattle Seahawks Odds

• Opening point spread: Packers -2.5
• Opening moneyline: Packers TBA/Seahawks TBA
• Opening total: Over/Under 47 points scored
• Time: 8:20 p.m. ET Sunday (NBC)

UPDATE 11 P.M. ET SUNDAY: Green Bay (9-4 SU/7-6 ATS) got into a track meet at Detroit in the Week 14 Thursday nighter. But the Packers couldn't quite get to the finish line, losing 34-31 on a final-seconds field goal. The Pack pushed as 3-point underdogs.

The setback ended a 7-1 SU surge by Green Bay (4-4 ATS).

Seattle (8-5 SU/6-6-1 ATS) has won four in row SU and ATS to surge ahead in the NFC West. In Week 14, the Seahawks closed as 3-point road 'dogs vs. Arizona and won outright 30-18.

The SuperBook opened the Pack -2.5 for the Sunday night game in the NFL odds Week 15 market.

"Seattle is in the driver's seat to win the division after today’s win at Arizona. Green Bay has been playing great offensively, and I expect the public to heavily back the Packers in this game, in this time slot," SuperBook executive director John Murray said.

Chicago Bears vs. Minnesota Vikings Odds

• Opening point spread: Vikings -7
• Opening moneyline: Vikings TBA/Bears TBA
• Opening total: Over/Under 43.5 points scored
• Time: 8 p.m. ET Monday (ABC)

UPDATE 11 P.M. ET SUNDAY: Minnesota (11-2 SU/8-4-1 ATS) is on a six-game win streak as it tries to keep pace with Detroit. The Vikings doubled up Atlanta 42-21 as 6-point home favorites.

Chicago (4-9 SU/7-5-1 ATS) has completely fallen off the map after starting 4-2 SU and ATS. In Week 14, the Bears were trendy 3-point road underdogs and got drubbed by injury-riddled San Francisco 38-13.

Chicago is on an 0-7 SU/2-4-1 ATS slide.

Minnesota opened as 7-point chalk in The SuperBook's Week 15 NFL odds.

"The Vikings just keep winning, week after week. They will close a lot of moneyline parlays," SuperBook executive director John Murray said. "We did see some sharp money on Chicago +7 and moved down to 6.5."

Atlanta Falcons vs. Las Vegas Raiders Odds

• Opening point spread: Falcons -4.5
• Opening moneyline: Falcons TBA/Raiders TBA
• Opening total: Over/Under 42 points scored
• Time: 8:30 p.m. ET Monday (ESPN)

UPDATE 11 P.M. ET SUNDAY: Atlanta (6-7 SU/5-8 ATS) is on an ill-timed 0-4 SU and ATS slide. In Week 14, the Falcons got rolled at Minnesota 42-21 catching 6 points.

Las Vegas (2-11 SU/4-9 ATS) is far worse off than Atlanta. The Raiders are an 0-9 SU purge, going 3-6 ATS in that stretch. Las Vegas was getting 6.5 points at Tampa Bay in Week 13 and lost 28-13.

Falcons-Raiders opened at Atlanta -4.5 and dipped to -4 tonight in The SuperBook's NFL Week 15 odds. The total was more on the move, going from 42 to 42.5, then 43.5.

In-Progress Games for NFL Week 15

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Completed Games for NFL Week 15

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson