NFL Odds Week 16: Cardinals vs Bears Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

2 minute read

Week 16 of the NFL season continues with a meaningful NFC North clash between the Detroit Lions and Minnesota Vikings. The betting odds see Chicago as a 4.5-point favorite in the aftermath of a heartbreaking loss to Cleveland last week. Coverage begins from Soldier Field in Chicago on Sunday, December 24 at 4:25 p.m. ET on FOX.

Here's everything you need to know about the NFL odds for Week 16: Cardinals vs Bears lines, spreads, betting trends and more.

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Arizona Cardinals vs Chicago Bears Odds

• Opening point spread: Bears -3.5
• Opening moneyline: Bears -220/Cardinals +180
• Opening total: Over/Under 45.5 points scored
• Time: 4:25 p.m. ET Sunday (FOX)

UPDATE 4:15 P.M. ET SUNDAY: Chicago is a 4.5-point favorite at BetMGM, minutes before kickoff. That's where this line opened a week ago, before falling to -4 Wednesday and -3.5 (-120) briefly Friday. The Bears then went to -4 again and this afternoon returned to -4.5.

Tickets and money are almost dead even on the spread, with a slight lean toward underdog Arizona. On the moneyline, tickets are split 50/50, but money is 2/1 Bears.

UPDATE 1:30 P.M. ET FRIDAY: The Bears slid from -4.5 to -4 Wednesday at BetMGM and are now -4 (-105). Chicago is netting 55% of spread bets/61% of spread dollars.

BetMGM opened the total at 44.5 and on Wednesday made moves to 44/43.5. This afternoon, it's down to 43, with 79% of bets/95% of cash on the Under.

UPDATE 10 P.M. ET SUNDAY: Chicago's two-game SU and three-game ATS run ended in Week 15. The Bears (5-9 SU/6-7-1 ATS) went up 17-7 midway through the third quarter at Cleveland, but ultimately lost 20-17 as 2.5-point underdogs.

Arizona (3-11 SU/7-7 ATS) fell to San Francisco 45-29 getting 12.5 points at home.

The Cards-Bears line is on the move early, with Chicago advancing to -4/-4.5 within a few minutes tonight. The total is down a point to 44.5 at The SuperBook.

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Week 16 Report containing spreads, lines, and trends for every NFL matchup.

Cardinals vs Bears Pick, Prediction

Action Network NFL betting expert Brandon Anderson offers this prediction:

Check back soon for picks!

Pick: TBD

For more NFL picks, check out Action Network's NFL Week 16: How to Bet Every Game & Every Team.

The One Stat to Know About Cardinals vs Bears

Action Network NFL researcher Evan Abrams offers his top betting stat:

Check back soon for betting stats!

For more NFL betting stats, check out Action Network's NFL Week 16 Betting Trends, Stats, Notes.

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Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson