NFL Odds Week 4: Lions vs Packers Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline
Packers vs
Lions
+2.5 (-115)
-2.5 (-105)
o44.5 (-115)
u44.5 (-105)
+114
-134

Week 4 of the NFL season kicks off at Lambeau Field in Green Bay with an important NFC North battle between the Lions and Packers. Both teams seek their third win of the season on Thursday, September 28 as things kick off at 8:15 p.m. ET on Amazon Prime.

Here's everything you need to know about the NFL odds for Week 4 Lions vs. Packers: the opening lines, spreads, betting trends and more. Check back regularly for updates.

Detroit Lions vs Green Bay Packers Odds

The Lions seek their second road win of the season on Thursday. (Getty)
  • Opening point spread: Lions -2
  • Opening moneyline: Lions -125/Packers +105
  • Opening total: Over/Under 44.5 points scored
  • Time: 8:15 p.m. ET Thursday (Prime)

UPDATE 7:30 P.M. ET THURSDAY: With kickoff looming, Detroit is laying 2.5 points in the NFL odds Week 4 market at PointsBet, a Fanatics Experience. The Lions opened -2 Sunday night and got as low as -1 a few times during the week before advancing to -2.5 this afternoon.

Point-spread ticket count is 4/1 and spread money 5/1 on the road favorite Lions.

The total opened at 44.5, peaked at 46.5 early Wednesday, then dialed down to 44.5 again a couple times today. It's now 45.5 on almost dead-even two-way action at PointsBet.

UPDATE 9 P.M. ET WEDNESDAY: This number has toggled around in TwinSpires Sportsbook's NFL odds Week 4 market. Last week's lookahead line was Packers -1.5, but when the game opened Sunday night, it was Lions -2.

Earlier today, the number was Lions -1, and TwinSpires is now splitting the difference at Detroit -1.5. Green Bay is taking 63% of early tickets/59% of early money.

"Green Bay as a slight home 'dog vs. the Lions is hard to pass up. We'll need the Lions on Thursday Night Football," TwinSpires director of retail sports Zachary Lucas said.

TwinSpires' total is up a point to 46, with 60% of tickets/55% of money on the Over.

UPDATE 10 P.M. ET SUNDAY: Detroit (2-1 SU and ATS) bounced back from its Week 2 home loss against Seattle. The Lions went off as 3.5-point home favorites and beat Atlanta 20-6.

Green Bay (2-1 SU/3-0 ATS) rallied from a 17-0 fourth-quarter deficit to top New Orleans. The Packers squeaked out an 18-17 victory to cash as 1.5-point home underdogs.

The SuperBook hasn't moved off Detroit -2 tonight.

"We closed at a pick in [last week's] lookahead, but re-opened Lions -2 and with a lower total, after Detroit's defense looked much better today," SuperBook risk supervisor Chase Michaelson said tonight. "Green Bay's comeback win was less impressive. It's hard to know what we'll need here, because the public isn't sure about Jordan Love yet."

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Week 4 Report containing spreads, lines, and trends for every NFL matchup.

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