NFL Odds Week 5: Bengals vs Cardinals Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline
Cardinals vs
Bengals
+3 (-102)
-3 (-120)
o45.5 (-114)
u45.5 (-106)
+148
-176

The Week 5 NFL betting odds show the Bengals as a three-point road favorite against the Cardinals. Coverage begins from State Farm Stadium in Glendale on Sunday, October 8 at 4:05 p.m. ET on FOX.

Here's everything you need to know about the NFL odds for Week 5 Bengals vs Cardinals: the opening lines, spreads, betting trends and more. Check back regularly for updates.

Cincinnati Bengals vs Arizona Cardinals Odds

The Cardinals own a 2-0 ATS record at home this season. (Getty)
  • Opening point spread: Bengals -5
  • Opening moneyline: Bengals -165/Cardinals +142
  • Opening total: Over/Under 42 points scored
  • Time: 4:05 p.m. ET Sunday (FOX)

UPDATE 4 P.M. ET WEDNESDAY: Interestingly, TwinSpires' lookahead line on this game was Cincinnati -8.5. But with hobbled Joe Burrow and the Bengals struggling, the line opened Sunday night at Bengals -5 and is already down to -3.

The Cardinals, who are 3-1 ATS and could very easily be 4-0 ATS, are getting 59% of early tickets/66% of early dollars on the spread.

"Bettors are out on the Bengals after another abysmal performance. The Cardinals have been the trendy team this year to bet," Lucas said.

TwinSpires' total is already up to 2 points to 44.5, with a stop at 43.5 along the way. The Over is drawing 54% of tickets/63% of money.

UPDATE 11 P.M. ET SUNDAY: Cincinnati reached the Super Bowl two seasons ago and the AFC Championship Game last season. But the Bengals (1-3 SU/0-3-1 ATS) haven't gotten much done on the field or for bettors so far this season.

In Week 4, QB Joe Burrow was bottled up by Tennessee in the Bengals' 27-3 loss giving 2.5 points on the road.

Arizona (1-3 SU/3-1 ATS) had its three-game season-opening ATS streak halted, though just barely, at San Francisco. The Cards, 14.5-point road pups, gave up a TD with two minutes remaining in a 35-16 loss.

The first move on Bengals-Cards was toward Arizona at the SuperBook. Cincy is now at -4.5, while the total is up a half-point to 42.5.

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Week 5 Report containing spreads, lines, and trends for every NFL matchup.

Bengals vs Cardinals Pick, Prediction

Action Network NFL betting expert Brandon Anderson offers this prediction:

Joe Burrow is expected to play, but he sure hasn't looked himself. By many of the fancy, advanced all-in-one metrics, Burrow has been the worst quarterback in football.

To that end, you won't find any reliable in-season metric telling you the Bengals should be favored. The Cardinals have been flat out better, particularly Drew Petzing's offense, which ranks top six in both passing and rushing DVOA.

The Cardinals offense continues to make magic happen, and Dobbs has been terrific. One way Petzing has unleashed Dobbs is as a runner. He's run for 41, 55 and 48 yards in the past three games and I don't think books have caught up yet.

Pick: Josh Dobbs Over 21.5 Rushing Yards (-110)

For more NFL Week 5 picks, check out Action Network's NFL Week 5: How to Bet Every Game & Every Team.

The One Stat to Know About Bengals vs Cardinals

Action Network NFL researcher Evan Abrams offers his top betting stat:

The Cardinals are in a good spot this week. They were double-digit underdogs last week but didn’t cover the spread. Over the last 20 years, teams that are listed as an underdog in their next game are 133-93-5 ATS (59%).

For more NFL Week 5 betting stats, check out Action Network's NFL Week 5 Betting Trends, Stats, Notes.

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