NFL Odds Week 5: Eagles vs Rams Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

3 minute read

The Eagles travel to Los Angeles in Week 5 of the NFL to face the Rams. The betting odds have Philadelphia as 3.5-point road favorites, seeking a 5-0 start. Coverage begins from SoFi Stadium in Inglewood on Sunday, October 8 at 4:05 p.m. ET on FOX.

Here's everything you need to know about the NFL odds for Week 5 Eagles vs Rams: the opening lines, spreads, betting trends and more. Check back regularly for updates.

Philadelphia Eagles vs Los Angeles Rams Odds

• Opening point spread: Eagles -4.5
• Opening moneyline: Eagles -220/Rams +180
• Opening total: Over/Under 46.5 points scored
• Time: 4:05 p.m. ET Sunday (FOX)

UPDATE 5 P.M. ET WEDNESDAY: The Eagles are up a notch in TwinSpires' NFL odds Week 5 market, moving from -4 to -4.5. Philly is attracting 58% of early spread tickets/64% of early spread cash.

"This is the first game this year that sharp action isn't on the Eagles' opponent," Lucas said. "The Rams will likely be a sizable need by kickoff."

TwinSpires' total opened at 49.5 and is up a point to 50.5, with a stop at 50 along the way. Ticket count is almost 2/1 and money 2.5/1 on the Over.

UPDATE 11 P.M. ET SUNDAY: Philadelphia (4-0 SU/2-1-1 ATS) remained perfect on the field, but barely so. The Eagles gave up a final-seconds TD at Washington, getting forced into overtime tied at 31. Philly got away with a 34-31 victory, but failed to cover as 8.5-point home chalk.

Los Angeles (2-2 SU/3-0-1 ATS) also landed in overtime, blowing a 23-8 fourth-quarter lead at Indianapolis and ending regulation tied at 23. The Rams then won 29-23 as 1-point road favorites.

"It's been Eagles and Over so far, and I think we'll see that continue," Degnon said. "A Rams upset win will most likely be our best outcome here."

Philly remains -4.5 at The SuperBook, but the total crept up to 47 tonight.

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Week 5 Report containing spreads, lines, and trends for every NFL matchup.

Eagles vs Rams Pick, Prediction

Action Network NFL betting expert Brandon Anderson offers this prediction:

This is one of those games the Eagles win in the trenches. You might remember Matt Stafford getting eaten alive when LA's offensive line had no chance in a Monday night game against the Bengals, so imagine what Jalen Carter and all Philadelphia's pass rushers will do. The Eagles also shut down the run game as they're No. 1 in Run Defense DVOA, and Sean McVay's offense is predicated on the run.

The other side of things is the big mismatch. The Rams offense has been impressive, but the defense just doesn't have much talent and has been especially poor against the run. That's the sort of defense D'Andre Swift should chew up. Trust the dominant line play.

The Rams have been better than expected, but that's just buying us value on the line. This was Philadelphia -6.5 before the season, so we're getting a free field goal now for an unbeaten team, just because of Stafford and Nacua? I don't buy it. There will be a time to fade the Eagles, but not in a matchup they should dominate in the trenches. Grab -3.5 if you can get it, but I'll play to -4.5 as needed.

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Pick: Eagles -4 (-110)

For more NFL Week 5 picks, check out Action Network's NFL Week 5: How to Bet Every Game & Every Team.

The One Stat to Know About Eagles vs Rams

Action Network NFL researcher Evan Abrams offers his top betting stat:

This week, the Rams become the third team in the last 20 years to be a home underdog of more than a FG without an ATS loss on the season in their fifth game or later. The other two: 2022 Falcons +3.5 (won outright) and the 2015 Steelers +5.5 (won outright).

For more NFL Week 5 betting stats, check out Action Network's NFL Week 5 Betting Trends, Stats, Notes.

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Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson