NFL Odds Week 6: Cowboys vs Chargers Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

3 minute read

The final game of the NFL Week 6 card takes place in Los Angeles as the Chargers host the Cowboys. The odds favor Dallas by two points as they look to rebound off a blowout loss at San Francisco. Catch all the action live from SoFi Stadium on Monday, October 16 at 8:15 p.m. ET on ESPN.

Here's everything you need to know about the NFL odds for Week 6 Cowboys vs Chargers: the opening lines, spreads, betting trends and more. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

Dallas Cowboys vs Los Angeles Chargers Odds

• Opening point spread: Cowboys -3 (even)
• Opening moneyline: Cowboys -140/Chargers +120
• Opening total: Over/Under 47.5 points scored
• Time: 8:15 p.m. ET Monday (ABC/ESPN)

UPDATE 4:30 P.M. ET MONDAY: At PointsBet, a Fanatics Experience, Los Angeles opened as a 1-point home favorite on Oct. 8. But within just minutes, the number jumped the fence to Dallas -1.5, and it went to -2 within a couple of hours.

The Cowboys proceeded to reach -2.5 a couple times by midweek. Then the line toggled between -2 and -1.5 several times from Thursday through this morning, before dipping to Dallas -1 this afternoon. The Cowboys are now -1.5.

Although the number has moved toward the Chargers, the Cowboys are still seeing 61% of spread tickets/67% of spread dollars. Dallas is also taking 56% of moneyline bets/64% of moneyline cash.

The total shot from 47.5 to 51.5 by Tuesday at PointsBet, with multiple stops along the way. Since then, it's mostly bounced between 51 and 50.5, and it's now 50.5. Ticket count is almost dead even, but 93% of money is on the Under, and PointsBet indicated that skew is because of some large Under wagers.

UPDATE 5:30 P.M. ET WEDNESDAY: Dallas stuck at TwinSpires' opener of -2 until this afternoon, then crept up to -2.5. Los Angeles is netting 56% of early spread tickets/59% of early spread dollars.

"The Cowboys' blowout loss is still fresh in the minds of bettors," TwinSpires' Zachary Lucas said, alluding to Dallas' loss at San Francisco. "Los Angeles is shaping up to be a trendy 'dog."

The total climbed from 49.5 to 50.5, with tickets 3/1-plus and money 4/1 on the Over.

"It's all Over money. Both teams can score and haven't been able to defend recently," Lucas said.

UPDATE 11 P.M. ET SUNDAY: Prior to the Week 5 Sunday night game between Dallas and San Francisco, The SuperBook opened the Cowboys -3 (even) vs. the Chargers in the NFL odds Week 6 market.

The Cowboys-Chargers line then came off the board once Cowboys-49ers kicked off. Based on Sunday's result, don't be surprised if the Cowboys-Chargers line shortens when it reposts Monday morning.

Dallas (3-2 SU and ATS) got boat-raced by San Fran 42-10 as a 3.5-point road underdog.

Los Angeles (2-2 SU and ATS) won and cashed in Weeks 3 and 4, after losing and failing to cover in Weeks 1 and 2. The Chargers, who had a Week 5 bye, topped the Raiders 24-17 giving 6.5 points at home in Week 4.

"There was sharp money on Dallas [last] week on this game that pushed us from Cowboys -2.5 to -3," Michaelson said, alluding to The SuperBook's lookahead line.

With that in mind, The SuperBook opened Dallas -3 tonight, but that's almost certain to change when the number goes back up Monday morning.

"This will go to some variation of 2.5," Michaelson said, while noting he still expects plenty of public play on the Cowboys. "We will need the Chargers in a standalone spot."

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Week 6 Report containing spreads, lines, and trends for every NFL matchup.

Cowboys vs Chargers Pick, Prediction

Action Network NFL betting expert Brandon Anderson offers this prediction:

Check back soon for picks!

Pick: TBD

For more NFL picks, check out Action Network's NFL Week 6: How to Bet Every Game & Every Team.

The One Stat to Know About Cowboys vs Chargers

Action Network NFL researcher Evan Abrams offers his top betting stat:

Check back soon for betting stats!

For more NFL betting stats, check out Action Network's NFL Week 6 Betting Trends, Stats, Notes.

Where to place a bet this NFL Season?

• Use our exclusive BetMGM Bonus Code VIBONUS1600 to unlock BetMGM's welcome offer for new sportsbook users!
• Compare the latest NFL Odds from the best sportsbooks before placing a bet on this week's games.
• Sports betting is live in North Carolina! Check out our list of North Carolina Sportsbooks and get ready for the NFL season.
• Our DraftKings Promo Code earns users $150 in bonus bets when you bet $5. Sign up today!

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson