NFL Odds Week 6: Lions vs Buccaneers Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

2 minute read

In Week 6 of the NFL season, the Lions look to stay hot as they travel to Tampa to face the Buccaneers. The odds favor Detroit, who is a three-point road favorite. Catch all the action live from Raymond James Stadium on Sunday, October 15 at 4:25 p.m. ET on FOX.

Here's everything you need to know about the NFL odds for Week 6 Lions vs Buccaneers: the opening lines, spreads, betting trends and more. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

Detroit Lions vs Tampa Bay Buccaneers Odds

• Opening point spread: Lions -3 (-120)
• Opening moneyline: Lions -180/Buccaneers +150
• Opening total: Over/Under 45.5 points scored
• Time: 4:25 p.m. ET Sunday (FOX)

UPDATE 1 P.M. ET SUNDAY: The Lions have been at -3 all week in Caesars Sports' NFL odds Week 6 market. Detroit opened -3 (-120), then adjusted to -3 (-115) Friday and -3 (-105) in the past 30 minutes.

Detroit is getting 77% of spread bets, but spread money is closer, at 57% on the Lions.

The total steadily made its way down from 45.5 to 42.5 by Thursday. Late this morning, the number upped to 43, then went to 43.5 in the past hour. Current Caesars splits aren't available.

UPDATE 5:30 P.M. ET WEDNESDAY: Detroit opened -3 and stuck there until this afternoon, nudging up to -3.5 in TwinSpires' NFL odds Week 6 market. Spread tickets are almost 3/1 and spread money beyond 2/1 early on.

"The Lions are very popular road chalk this week. We're already seeing 7/1 tickets and 8/1 money on Lions moneyline," TwinSpires' Zachary Lucas said.

The total is down 2 points to 43.5, with 59% of tickets on the Over/64% of money on the Under.

"Sharp play on Under 45.5," Lucas said.

UPDATE 11 P.M. ET SUNDAY: Detroit (4-1 SU and ATS) has been red-hot since the middle of last season, going 12-3 SU/13-2 ATS. Week 5 against Carolina was more of the same, with the Lions rolling 42-24 as 9.5-point home favorites.

Baker Mayfield and Tampa Bay are a perhaps surprising 3-1 SU and ATS. The Bucs are coming off their bye week, after breezing by New Orleans 26-9 as 4.5-point road underdogs.

The Lions-Bucs total went from 45.5 to 45 and back to 45.5 tonight at The SuperBook.

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Week 6 Report containing spreads, lines, and trends for every NFL matchup.

Lions vs Buccaneers Pick, Prediction

Action Network NFL betting expert Brandon Anderson offers this prediction: I liked the under initially and like it even more with all the Detroit injuries, but we missed the best of the line since this was at 45.5 last Sunday, before coming down to 42.5 earlier this week.

I played a half unit assuming it might drop below key total numbers of 42 and 41, but on Sunday morning, you can actually get the slightly better line of 43.5 at FanDuel.

Pick: Under 43.5

For more NFL picks, check out Action Network's NFL Week 6: How to Bet Every Game & Every Team.

The One Stat to Know About Lions vs Buccaneers

Action Network NFL researcher Evan Abrams offers his top betting stat: The Lions are 27-12 ATS since the start of the 2021 season, most profitable team ATS in the NFL ($1,262).

For more NFL betting stats, check out Action Network's NFL Week 6 Betting Trends, Stats, Notes.

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Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson