2025 March Madness: Final Four Odds, Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

4 minute read

Final Four odds are now on the board, as March Madness surges toward April. And the No. 1 seeds are the only ones left on the dance floor.

It'll be Florida vs. Auburn in Saturday's first semifinal. Then it's fellow No. 1s Houston vs. Auburn in the second semi on the Final Four odds board.

Here's everything you need to know about college basketball odds for NCAA Tournament Final Four matchups: lines, spreads and betting trends on both games. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

Final Four Odds

Florida vs. Auburn Odds

• Opening point spread: Florida -2.5
• Opening moneyline: Florida -142/Auburn +120
• Opening total: Over/Under 164.5 points scored
• Time: 6:09 p.m. ET Saturday (CBS)

UPDATE 4 P.M. ET MONDAY: Early on in DraftKings' March Madness Final Four odds market, it's been the total on the move. On Sunday evening, the total opened at 162.5, and it fell to 160.5 within a few hours.

"The total has dropped, and I think that's due to a couple of things. One, whether Johni Broome (elbow) is 100%. And two, if you look at the tournament trend, 57% of games have gone Under," DraftKings director of sportsbook operations Johnny Avello said.

There's a third factor, as well, that often comes into play as the stakes get higher.

"This being a Final Four game, maybe things tighten up a little bit, the players are little tighter early in games, so maybe not as much scoring," Avello said.

The spread hasn't moved off Florida -2.5, save for a modest juice adjustment from Gators -2.5 flat to -2.5 (-115).

"There's more money on Florida, but not that much more," Avello said. "These two teams know each other. Trying to pick the winner is harder."

UPDATE 11 P.M. ET SUNDAY: Florida vs. Auburn has been on DraftKings' Final 4 odds board for 3.5 hours and hasn't budged off Gators -2.5. That's despite early action landing solidly on the favorite.

Early spread tickets are running 3/1 and early spread money 7/1 on Florida. Moneyline play is tilted toward the Gators, as well, with tickets almost 2/1 and money beyond 3/1.

The total dipped from 162.5 to 161.5 right out of the gate, then in the past hour fell to 160.5. Ticket count is 2.5/1 money almost 5/1 on the Under.

These SEC rivals met once in the regular season. Florida was a hefty 11-point road underdog and notched a 90-81 upset on Feb. 8. The Over hit on a total of 156.5.

UPDATE 7:30 P.M. ET SUNDAY: With 3:14 remaining in regulation Saturday night, No. 1 seed Florida was in a 75-66 hole vs. No. 3 seed Texas Tech. But the Gators made four consecutive 3-pointers, and the Red Raiders missed the front end of two one-and-ones.

When the dust settled, Florida escaped with an 84-79 victory as 6.5-point favorites in the West Region final. The Gators (34-4 SU/27-11 ATS) are on a 10-game win streak and are 16-1 SU/13-4 ATS in their last 17 games.

On Sunday, Auburn made it 4-for-4 for No. 1 seeds. The Tigers (32-5 SU/21-16 ATS) topped No. 2 seed Michigan State 70-64, narrowly covering as 5.5 point favorites.

Player of the Year candidate Johni Broome suffered an elbow injury midway through the second half. But X-rays were negative, and he returned to the court in the final minutes.

Auburn is on a modest 3-0 ATS upswing, which comes after a five-game ATS slide that was part of a 2-7 ATS stretch.

Florida opened as 2.5-point chalk in DraftKings Sportsbook's Final Four odds, with no movement in the first few minutes. However, the total was quickly on the move, dropping from 164.5 to 161.5.

Check back later for odds and action updates in this matchup.

Houston vs. Duke Odds

• Opening point spread: Duke -4.5 (-115)
• Opening moneyline: Duke -198/Houston _+164
• Opening total: Over/Under 136.5 points scored
• Time: 8:49 p.m. ET Saturday (CBS)

UPDATE 4 P.M. ET MONDAY: Unlike Florida vs. Auburn, DraftKings Sportsbook's Johnny Avello said early spread play on this matchup is much more clear-cut. Duke opened -4.5 and has already made a couple trips to -5.5, currently sitting at -5.5 (-105).

"We've taken a little bit more Duke play here. You can expect Duke to continue to take money, on the spread, the moneyline and on moneyline parlays," Avello said.

DraftKings total is steady at 136.5 in Final Four odds.

UPDATE 7:30 P.M. ET SUNDAY: As noted below, Duke opened -4.5 (-115) in March Madness Final Four odds at DraftKings Sportsbook. The Blue Devils briefly advanced to -5.5 (-102), then returned to -4.5 (-118).

But it's all Duke early on the point spread, at 84% of bets/94% of money. Duke moneyline is practically just as popular, with the Blue Devils seeing 79% of early bets/94% of early dollars.

DK's total hasn't budged off 136.5, even with 76% of bets/78% of cash on the Over so far.

UPDATE 5 P.M. ET SUNDAY: No. 1 seed Duke (35-3 SU/26-12 ATS) made it 2-for-2 for No. 1 seeds Saturday. The Blue Devils, 7-point favorites in the East Region final, stifled No. 2 seed Alabama in an 85-65 victory.

Duke brings a 15-game win streak with it to San Antonio, going 11-4 ATS in that stretch.

Houston then made it 3-for-3 for No. 1 seeds. The Cougars put the clamps on No. 2 Tennessee in the first half and kept the Vols at arms length the rest of the way.

Houston (34-4 SU/20-17-1 ATS) led 34-15 at halftime and rolled to a 69-50 victory as 2.5-point favorites in today's Midwest Region final. The Cougars are on a 15-game win streak, part of a 30-1 overall SU spree

DraftKings Sportsbook opened Duke -4.5 (-115) a half hour ago, with no movement so far. Likewise, the total is stable at 136.5. Check back later for updates on this matchup in Final Four odds.

Final Four Picks & Predictions

If you're looking for Final Four picks and predictions from our expert handicappers, check out our college basketball picks page for the latest. And don't forget about VI Premium as well!

Odds For Final Four Teams To Win NCAA Tournament

See below the odds for the Final Four teams to win the Big Dance 🏆

National Championship Winner Odds

Time	Bet365	BetMGM	DraftKings	Caesars	FanDuel	BallyBet	RiversCasino
	›	›	›	›	›	›	›
Duke	+100	+100	+105	+100	+220	-110	-110
Florida	+280	+275	+300	+300	+410	+270	+270
Houston	+450	+425	+400	+425	+500	+400	+400
Auburn	+500	+525	+500	+525	+500	+450	+450
See All
Tennessee					+1600
Alabama					+1600
Texas Tech					+2100
Michigan State					+2100
Maryland					+2700
Kentucky					+6000
BYU					+7000
Michigan					+7000
Purdue					+7000
Ole Miss					+8000
Arkansas					+10000

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson