NFL Odds Week 18: Lines, Spreads, Betting Trends For All 16 Games

NFL Odds Week 18: Lines, Spreads, Betting Trends For All 16 Games

2024-25 NFL Odds Week 18

Matchup Spread Total Moneyline
Ravens vs
Browns
-18 (-108)
+18 (-112)
o41.5 (-108)
u41.5 (-112)
-1800
+1000
Steelers vs
Bengals
+2 (-112)
-2 (-108)
o48 (-108)
u48 (-112)
+110
-130
Buccaneers vs
Saints
-13.5 (-112)
+13.5 (-108)
o43.5 (-110)
u43.5 (-110)
-900
+600
Patriots vs
Bills
+2.5 (-105)
-2.5 (-115)
o38 (-112)
u38 (-108)
+120
-142
Packers vs
Bears
-10 (-110)
+10 (-110)
o41 (-112)
u41 (-108)
-455
+350
Colts vs
Jaguars
-4.5 (-112)
+4.5 (-108)
o45 (-108)
u45 (-112)
-205
+170
Falcons vs
Panthers
-8 (-110)
+8 (-110)
o48 (-112)
u48 (-108)
-440
+340
Cowboys vs
Commanders
+5 (-112)
-5 (-108)
o44 (-108)
u44 (-112)
+185
-225
Titans vs
Texans
+1 (-115)
-1 (-105)
o38.5 (-108)
u38.5 (-112)
-110
-110
Eagles vs
Giants
-2 (-110)
+2 (-110)
o37.5 (-110)
u37.5 (-110)
-125
+105
Jets vs
Dolphins
+1 (-112)
-1 (-108)
o39 (-108)
u39 (-112)
-102
-118
Broncos vs
Chiefs
-10.5 (-108)
+10.5 (-112)
o40 (-108)
u40 (-112)
-575
+425
Raiders vs
Chargers
+4.5 (-108)
-4.5 (-112)
o41.5 (-105)
u41.5 (-115)
+160
-192
Rams vs
Seahawks
+6.5 (-108)
-6.5 (-112)
o38.5 (-112)
u38.5 (-108)
+210
-258
Cardinals vs
49ers
-4 (-108)
+4 (-112)
o42.5 (-110)
u42.5 (-110)
-198
+164
Lions vs
Vikings
-2.5 (-120)
+2.5 (even)
o56.5 (-110)
u56.5 (-110)
-148
+124

NFL odds for Week 18 are often a crap shoot, at best. It's hard to say who's going to play, who's going to rest and who's completely thrown in the towel.

From what we know, though, the marquee matchup in odds for NFL Week 18 is Minnesota Vikings vs. Detroit Lions. Plenty of other matchups have playoff implications, for qualifying and/or seeding.

Here’s everything you need to know about the NFL odds Week 18 market: opening lines, spreads and betting trends for every game, as multiple oddsmakers provide insights on Week 18 NFL odds and action. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

NFL Odds for Every Game of NFL Week 18

Cleveland Browns vs. Baltimore Ravens Odds

Matchup Spread Total Moneyline
Ravens vs
Browns
-17.5 (-108)
+17.5 (-112)
o41.5 (-108)
u41.5 (-112)
-1800
+1000
  • Opening point spread: Ravens -16.5
  • Opening moneyline: Ravens -1800/Browns +1100
  • Opening total: Over/Under 42.5 points scored
  • Time: 4:30 p.m. ET Saturday (ESPN/ABC)

UPDATE 10:30 P.M. ET SUNDAY: Baltimore (11-5 SU/9-6-1 ATS) controls its destiny for the AFC North title and likely No. 3 seed. In Week 17, the Ravens flattened Houston 31-2 giving 6.5 points on the road Christmas Day.

Cleveland was dealt its fifth consecutive SU and ATS loss in Week 18. The Browns (3-13 SU/5-11 ATS) managed only a second-quarter field goal in a 20-3 loss as 3-point home 'dogs vs. Miami.

Browns-Ravens opened at Baltimore -16.5 and sped to -17/-18 tonight in The SuperBook's NFL odds Week 18 market.

Cincinnati Bengals vs. Pittsburgh Steelers Odds

Matchup Spread Total Moneyline
Steelers vs
Bengals
+1.5 (-108)
-1.5 (-112)
o48.5 (-110)
u48.5 (-110)
+102
-122
  • Opening point spread: Bengals -2.5
  • Opening moneyline: Bengals -155/Steelers +135
  • Opening total: Over/Under 46.5points scored
  • Time: 8 p.m. ET Saturday (ESPN/ABC)

UPDATE 8 P.M. ET WEDNESDAY: Borgata Sports, a BetMGM property in Atlantic City, opened the Bengals -2.5. Early Steelers money pushed Cincy down to -1.5, and the line is now stable at -2.

Borgata sportsbook director Tom Gable noted the game's ramifications, with Cincinnati needing a win and help to get to the playoffs. Pittsburgh has lost three in a row SU and ATS.

"The good news for Pittsburgh is this Cincy defense isn’t on the same level as Philly, Baltimore and K.C., which were quite successful in not only shutting down the Pittsburgh defense, but also turning them over," Gable said.

Pittsburgh has motivation Saturday night, as well.

"If Baltimore wins the early game on Saturday, the Steelers know that a win can secure the No. 5 seed and a playoff game against Houston, which is technically the opponent that every non-division winner would want to see first in the AFC playoffs," Gable said.

The total opened at 47.5 and is up to 48.5. 

UPDATE 10:30 P.M. ET SUNDAY: Pittsburgh (10-6 SU and ATS) has at least a Wild Card slot secured, but could still take the AFC North, with a win and some help. In Week 17, the Steelers lost to Kansas City 29-10 catching 2 points at home on Christmas Day.

To win the division, Pittsburgh needs to beat Cincy and have Baltimore lose to visiting Cleveland. The Steelers are on an 0-3 SU and ATS skid.

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Cincinnati (8-8 SU/10-6 ATS) was left for dead after falling to 4-8 through a dozen games. But the Bengals, in must-win situations every week, are on a 4-0 SU and ATS surge and still alive.

In Week 17, Cincy was 3.5-point home chalk vs. Denver. The Bengals got dragged to overtime when the Broncos tied it at 24 on a waning-seconds touchdown. But Joe Burrow & Co. got a TD in the final minute of the extra frame to win 30-24.

The SuperBook opened Cincinnati -2.5 and adjusted to -2.5 (-120) within an hour tonight. The total saw a bigger move, going straight from 46.5 to 48 within 15 minutes in Week 18 NFL odds.

"The Bengals need a lot to go right to make the playoffs, because of all the games they gave away early in the season. But they’re a very dangerous team," SuperBook vice president John Murray said. "I’m sure the top seeds will be happy to see Cincinnati not get into the field next week."

Indeed, likely no team wants to face Joe Burrow.

Washington Commanders vs. Dallas Cowboys Odds

Matchup Spread Total Moneyline
Cowboys vs
Commanders
+4.5 (-110)
-4.5 (-110)
o43.5 (-115)
u43.5 (-105)
+180
-218
  • Opening point spread: Commanders -4
  • Opening moneyline: Commanders -155/Cowboys +135
  • Opening total: Over/Under 45.5 points scored
  • Time: 1 p.m. ET Sunday (FOX)

UPDATE 8 P.M. ET WEDNESDAY: The Commanders are out to -4.5 from a -3 opener in Borgata Sports' NFL odds Week 18 market.

"It’s been mostly Washington money here early," Borgata sportsbook director Tom Gable said. "The Commanders’ [Wild Card] opponent won’t be known until everything settles on Sunday. But they definitely don’t want to lose this one and fall to the 7 seed, which would make them head to Philly first to play a division foe."

The total is down to 44 from a 45.5 opener.

UPDATE 10:30 P.M. ET SUNDAY: Washington (10-5 SU/9-5-1 ATS) is playing right now in the Week 17 Sunday night game, hosting Atlanta.

Dallas (7-8 SU and ATS) got to face a Philly team missing Jalen Hurts (concussion protocol). It hardly mattered. The Cowboys got thumped 40-7 by the combination of backups Kenny Pickett and Tanner McKee. That ended a 4-1 SU and ATS upswing for Dallas.

Commanders-Cowboys opened at Washington -4 at The SuperBook. The game was taken off the board once Falcons-Commanders kicked off. Commanders-Cowboys will go back up Monday morning.

New York Giants vs. Philadelphia Eagles Odds

The Eagles hope to have Jalen Hurts in Week 18 vs. the Giants. (Getty)
Matchup Spread Total Moneyline
Eagles vs
Giants
-2.5 (-108)
+2.5 (-112)
o37.5 (-110)
u37.5 (-110)
-142
+120
  • Opening point spread: Eagles -5
  • Opening moneyline: Eagles -175/Giants +155
  • Opening total: Over/Under 39 points scored
  • Time: 1 p.m. ET Sunday (CBS)

UPDATE 10:30 P.M. ET SUNDAY: Philadelphia (13-3 SU/10-6 ATS) had its 10-game SU run end in Week 16, but rebounded nicely in Week 17. Even without Jalen Hurts, who was in concussion protocol, and with backup Kenny Pickett (ribs) exiting in the third quarter vs. Dallas.

Philly was already up 24-7 when Pickett exited, and the Eagles went on to a 41-7 rout as 7.5-point home favorites.

New York (3-13 SU/5-11 ATS) opted against tanking for a shot at the No. 1 draft pick. The Giants were 7.5-point home underdogs and won a 45-33 shootout vs. Indianapolis. It was New York's first home win all season, in the final home game.

The Giants-Eagles line was on the move early in The SuperBook's Week 18 NFL odds. Philly opened -5 and quickly dipped to -4/-3, then settled at -3.5. The total nudged from 39 to 38.5.

Carolina Panthers vs. Atlanta Falcons Odds

Matchup Spread Total Moneyline
Falcons vs
Panthers
-8 (-110)
+8 (-110)
o48 (-112)
u48 (-108)
-440
+340
  • Opening point spread: Falcons -7.5
  • Opening moneyline: Falcons -420/Panthers +350
  • Opening total: Over/Under 48 points scored
  • Time: 1 p.m. ET Sunday (CBS)

UPDATE 10:30 P.M. ET SUNDAY: Atlanta (8-8 SU/7-9 ATS), behind Michael Penix Jr., took Washington to overtime in the Week 17 Sunday night game. But the Falcons then fell short 31-24 as 3.5-point road underdogs.

Atlanta needs to win and get help in Week 18 to reach the playoffs.

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Carolina (4-12 SU/7-9 ATS) was on a 6-1 ATS run entering Week 17. Tampa Bay put a halt to that, with the Panthers tumbling 48-14 as 10-point home pups.

The SuperBook opened Panthers-Falcons at Atlanta -7.5 tonight. Within an hour, the Falcons advanced to -8.5, then the game came off the board once Falcons-Commanders kicked off. Panthers-Falcons will go back up Monday morning.

New Orleans Saints vs. Tampa Bay Buccaneers Odds

Matchup Spread Total Moneyline
Buccaneers vs
Saints
-13.5 (-108)
+13.5 (-112)
o43.5 (-110)
u43.5 (-110)
-850
+575
  • Opening point spread: Buccaneers -13
  • Opening moneyline: Buccaneers -1200/Saints +750
  • Opening total: Over/Under 43.5 points scored
  • Time: 1 p.m. ET Sunday (FOX)

UPDATE 10:30 P.M. ET SUNDAY: Tampa Bay (9-7 SU/10-6 ATS) did what was necessary to stay in contention for the NFC South title. The Bucs steamrolled Carolina 48-14 laying 10 points at home, moving to 5-1 SU in their last six games.

New Orleans (5-10 SU and ATS) enters Week 18 on a three-game SU slide in a disappointing season. In Week 17, the Saints lost to Las Vegas 25-10 catching 1.5 points at home.

The SuperBook fully expects Tampa to roll, opening the Bucs -13. Within just a few minutes, that number went to Bucs -13.5/-14 in the NFL odds Week 18 market.

"The Bucs were big Commanders fans tonight," SuperBook vice president John Murray said, noting Washington's win over Atlanta put Tampa Bay in a very good spot for Week 18.

Chicago Bears vs. Green Bay Packers Odds

Jordan Love and the Packers are aiming for a better Wild Card seed. (Getty)
Matchup Spread Total Moneyline
Packers vs
Bears
-10 (-110)
+10 (-110)
o41 (-112)
u41 (-108)
-455
+350
  • Opening point spread: Packers -10
  • Opening moneyline: Packers -420/Bears +350
  • Opening total: Over/Under 43 points scored
  • Time: 1 p.m. ET Sunday (FOX)

UPDATE 10:30 P.M. ET SUNDAY: Green Bay (11-5 SU/9-7 ATS) saw its Week 17 rally at Minnesota come up just short. The Packers trailed 27-10 well into the fourth quarter, then got two touchdowns and one 2-point conversion while pulling within 27-25.

But that's where the score stayed, with the Packers failing to cash as 1-point underdogs. That ended a five-game spread-covering run by Green Bay.

Chicago (5-11 SU/8-7-1 ATS) hasn't won since Tyrique Stevenson mocked Washington fans in the waning seconds of a Week 8 game. Commanders QB Jayden Daniels followed moments later by completing a Hail Mary to beat the Bears 18-15.

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Chicago is now on an 10-game SU nosedive (3-6-1 ATS), after starting the season 4-2 SU. In the Week 17 Thursday nighter, the Bears managed only a second-quarter field goal vs. Seattle, losing an eyesore of a game 6-3. But Chicago covered as a 4.5-point home 'dog.

The SuperBook opened Bears-Packers at Green Bay -10 and dipped to -9.5/-9 in fairly short order tonight. The total was a bigger mover in the NFL odds Week 18 market. It tumbled from 43 to 39.5, with multiple stops along the way, before settling at 40.

Buffalo Bills vs. New England Patriots Odds

Matchup Spread Total Moneyline
Patriots vs
Bills
+3 (-118)
-3 (-102)
o38 (-112)
u38 (-108)
+120
-142
  • Opening point spread: Bills -3.5
  • Opening moneyline: Bills -155/Patriots +135
  • Opening total: Over/Under 41.5 points scored
  • Time: 1 p.m. ET Sunday (CBS)

UPDATE 10:30 P.M. ET SUNDAY: Buffalo (13-3 SU/10-6 ATS) clinched the AFC's No. 2 seed by winning for the 10th time in the last 11 games. The Bills boat-raced the New York Jets 40-14 giving 10 points at home.

New England (3-13 SU/6-9-1 ATS) takes a six-game losing streak into the final week of the season. The Patriots provided little resistance to the L.A. Chargers in Week 18, getting hammered 40-7 as 6-point home underdogs.

Buffalo has nothing more to play for, so The SuperBook opened the Bills as just 3.5-point road favorites. And Patriots backers jumped on that, as the line moved to Buffalo -1.5 within 10 minutes.

The Bills have since stabilized at -2.5.

Houston Texans vs. Tennessee Titans Odds

Matchup Spread Total Moneyline
Titans vs
Texans
+1 (-115)
-1 (-105)
o38.5 (-110)
u38.5 (-110)
-108
-112
  • Opening point spread: Titans -1
  • Opening moneyline: Titans -210/Texans +180
  • Opening total: Over/Under 36.5 points scored
  • Time: 1 p.m. ET Sunday (CBS)

UPDATE 10:30 P.M. ET SUNDAY: Houston (9-7 SU/6-10 ATS) is stumbling into the playoffs, assured of the No. 4 seed because the AFC South isn't good. There's a chance that all three AFC Wild Card teams could have better records than the Texans.

In Week 17, Houston mustered only a second-quarter safety while getting bashed by Baltimore 31-2 as a 6.5-point home underdog.

Tennessee (3-13 SU/2-14 ATS) heads to Week 18 on a five-game SU and ATS purge. In Week 17, the Titans were 1-point favorites at Jacksonville and lost 20-13. Tennessee has the NFL's worst spread-covering record.

The SuperBook doesn't expect Houston to play any key starters in Week 18. Tennessee opened -1, went straight to -3 within a few minutes and got to -5.5 in under 30 minutes. The Titans then stabilized at -4.5 tonight in the NFL odds Week 18 market.

Jacksonville Jaguars vs. Indianapolis Colts Odds

Matchup Spread Total Moneyline
Colts vs
Jaguars
-4.5 (-112)
+4.5 (-108)
o44.5 (-112)
u44.5 (-108)
-205
+170
  • Opening point spread: Colts -4.5
  • Opening moneyline: Colts -220/Jaguars +190
  • Opening total: Over/Under 44.5 points scored
  • Time: 1 p.m. ET Sunday (FOX)

UPDATE 10:30 P.M. ET SUNDAY: Indianapolis (7-9 SU/9-7 ATS) was a 7.5-point road fave vs. the New York Giants and needed only a win to keep playoff hopes alive. But the Colts weren't up to the task, losing a shootout 45-33.

Jacksonville halted a 1-8 SU nosedive in Week 17. The Jaguars (4-12 SU/9-7 ATS) were 1-point home 'dogs vs. Tennessee and won 20-13. That ended a 1-7 SU purge for Jacksonville.

Indy opened -4.5, quickly went to -5.5, then moved to -5 tonight in The SuperBook's NFL Week 18 odds.

Kansas City Chiefs vs. Denver Broncos Odds

Bo Nix and the Broncos need a win to guarantee a Wild Card bid. (Getty)
Matchup Spread Total Moneyline
Broncos vs
Chiefs
-10.5 (-108)
+10.5 (-112)
o39.5 (-112)
u39.5 (-108)
-575
+425
  • Opening point spread: Broncos -6.5
  • Opening moneyline: Broncos -550/Chiefs +425
  • Opening total: Over/Under 40 points scored
  • Time: 4:25 p.m. ET Sunday (CBS)

UPDATE 8 P.M. ET WEDNESDAY: Denver hit Borgata Sports' NFL Week 18 odds board as 9.5-point chalk and made a stop at -10 on teh way to -10.5.

"This is a win-and-in scenario for Denver. The good news for the Broncos is Andy Reid will rest the Chiefs’ starters, giving Carson Wentz the start at QB," Borgata sportsbook director Tom Gable said. "Early Denver money pushed this past 10. We will see if any K.C. money starts to come in, but it’s been mostly Denver thus far."

The total went from 38.5 to 39.5.

UPDATE 10:30 P.M. ET SUNDAY: Kansas City (15-1 SU/8-8 ATS) literally has nothing to play for in Week 18. The Chiefs locked up the AFC's No. 1 seed on Christmas Day in Pittsburgh. K.C. rolled to a 29-10 victory laying 2 points.

It was the Chiefs' sixth straight win and, perhaps more notably, their third straight spread-cover, after a seven-game ATS purge.

Denver (9-7 SU/11-5 ATS) blew a golden opportunity to wrap up the final playoff slot in the AFC. The Broncos took Cincinnati to overtime, but lost 30-24 in the final minute of the extra frame, failing to cash as 3.5-point road underdogs.

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Bo Nix & Co. are on an ill-timed two-game SU and ATS skid, after a 6-2 SU/7-1 ATS run got them into playoff contention. Now, Denver needs a win or tie vs. K.C. to get to the postseason for the first time since the 2015-16 season.

With K.C. having nothing to gain, The SuperBook opened Denver -6.5 in Week 18 NFL odds. The Broncos shot straight to -9.5 from there and briefly touched -10, before resettling at -9.5.

"This one moved around, getting up to Broncos -10, then taking sharp money on the 'dog and coming back to 9.5," SuperBook vice president John Murray said. "Surely the Broncos couldn’t lose at home to the Kansas City backups, right?"

The total opened at 40 and made a stop at 39.5 on the way to 38.5.

Miami Dolphins vs. New York Jets Odds

Matchup Spread Total Moneyline
Jets vs
Dolphins
+1 (-112)
-1 (-108)
o39 (-112)
u39 (-108)
-102
-118
  • Opening point spread: Dolphins -2.5
  • Opening moneyline: Dolphins -140/Jets +120
  • Opening total: Over/Under 42 points scored
  • Time: 4:25 p.m. ET Sunday (FOX)

UPDATE 8 P.M. ET WEDNESDAY: Miami nudged from -1.5 to -2 in Borgata Sports' Week 17 NFL odds.

"The Dolphins aren’t technically eliminated yet, but would need to win here against the Jets and hope that K.C.'s backups can get a win over Denver," Borgata sportsbook director Tom Gable said. ""Not a lot of action on the side in this game yet."

One potential positive that Gable noted: Miami will likely face a struggling Aaron Rodgers, who threw two interceptions and was sacked four times last week vs. Buffalo, before being taken out.

The total dropped from 41 to 39.

UPDATE 10:30 P.M. ET SUNDAY: New York (4-12 SU/5-11 ATS) saw its dismal season continue in Week 17. The Jets were 10-point underdogs and trailed 40-0 by early in the fourth quarter of a 40-14 blowout loss at Buffalo.

Miami (8-8 SU and ATS) got a Week 18 win to keep alive its slim playoff hopes. The Dolphins closed as 3-point favorites at Cleveland and won 20-3, despite not having QB Tua Tagovailoa (hip).

Dolphins-Jets opened at Miami -2.5 in The SuperBook's NFL Week 18 odds, with no movement so far. However, the total dropped from 42 to 40.5 tonight, then settled in at 41.

"The Dolphins could still get in the playoffs, but need help," SuperBook vice president John Murray said.

Los Angeles Chargers vs. Las Vegas Raiders Odds

Matchup Spread Total Moneyline
Raiders vs
Chargers
+5 (-110)
-5 (-110)
o41.5 (-105)
u41.5 (-115)
+180
-218
  • Opening point spread: Chargers -3.5
  • Opening moneyline: Chargers -240/Raiders +200
  • Opening total: Over/Under 42.5 points scored
  • Time: 4:25 p.m. ET Sunday (CBS)

UPDATE 11:30 P.M. ET SUNDAY: Los Angeles (10-6 SU/11-5 ATS) secured an AFC Wild Card bid in blowout fashion. The Chargers closed as 6-point favorites at New England and rumbled to a 40-7 victory.

L.A. has won two in a row after a 1-3 SU hiccup, and the Chargers are 8-2 ATS in their last 10 outings.

Las Vegas (4-12 SU/7-9 ATS) is on a modest two-game upswing, after dropping 10 in a row SU. The Raiders were 1.5-point favorites at New Orleans and notched a 25-10 victory.

Chargers-Raiders opened at L.A. -3.5 and moved out to -5.5 within 30 minutes. The Chargers are now -5. The total opened at 42.5 and fell to 40.5, with stops at each half-point along the way. It's now at 41.

Seattle Seahawks vs. Los Angeles Rams Odds

Matchup Spread Total Moneyline
Rams vs
Seahawks
+6.5 (-108)
-6.5 (-112)
o38.5 (-112)
u38.5 (-108)
+210
-258
  • Opening point spread: Rams -3
  • Opening moneyline: Rams TBA/Seahawks TBA
  • Opening total: Over/Under 44.5 points scored
  • Time: 4:25 p.m. ET Sunday (FOX)

UPDATE 8 P.M. ET WEDNESDAY: Borgata Sports opened L.A. -1.5, but this number has since made a seven-point swing.

"This is one is one of those games where news means everything to the spread," Borgata sportsbook director Tom Gable said. "The Seahawks are now up to 5.5 point favorites after [Rams] coach Sean McVay has decided to rest starters and potentially lose out on the No. 33 seed in the NFC.

"The Seahawks are officially eliminated, but will more than likely be facing Jimmy Garoppolo at QB, behind some backups on the offensive line."

UPDATE 10:30 P.M. ET SUNDAY: Los Angeles (10-6 SU/8-8 ATS) survived a slog against Arizona in Week 17. The Rams held on for a 13-9 victory, failing to cover as 6.5-point home favorites. That ended a 4-0 ATS run.

Still, L.A. is on a five-game SU win streak and is 9-2 SU/7-4 ATS in its last 11 games. More important, with Washington beating Atlanta in overtime Sunday night, that clinched a playoff spot for the Rams as NFC West champs.

Seattle (9-7 SU/6-9-1 ATS) temporarily kept its playoff hopes alive in Week 17, despite a dreadful performance at Chicago. The Seahawks closed as 4.5-point favorites and barely got beyond 4.5 points in total, winning a 6-3 rock fight Thursday night. There was no scoring in the second half.

However, the Commanders' win over the Falcons eliminated Seattle from playoff contention.

The Rams opened -3 in The SuperBook's NFL Week 18 odds, and the line went to -2.5 within a few minutes. The total saw more movement, going from 44.5 to 42.5/41.5 tonight.

Seahawks-Rams was taken off The SuperBook's board while the risk room awaited a result on Falcons-Commanders. Seahawks-Rams will go back up Monday morning, likely at a significantly different number, with L.A. having the division title in hand.

San Francisco 49ers vs. Arizona Cardinals Odds

Matchup Spread Total Moneyline
Cardinals vs
49ers
-4 (-108)
+4 (-112)
o42.5 (-110)
u42.5 (-110)
-198
+164
  • Opening point spread: 49ers -1.5
  • Opening moneyline: 49ers -110/Cardinals -110
  • Opening total: Over/Under 46.5 points scored
  • Time: 4:25 p.m. ET Sunday (FOX)

UPDATE 11:45 P.M. ET MONDAY: San Fran (6-10 SU/5-11 ATS) led the Week 17 Monday night game vs. Detroit 21-13 at halftime and 28-21 midway through the third quarter. But Brock Purdy threw two INTs from there, and the Niners lost 40-28 as 4-point home underdogs.

In a long season for the defending NFC champs, the 49ers are on slides of 1-6 SU/1-7 ATS. Further, Purdy suffered an apparent arm injury late against Detroit, so his status could be murky.

DraftKings Sportsbook opened 49ers-Cards at San Francisco -1 and was at Niners -1 (-105) prior to the Detroit-San Fran game. But with the Purdy injury, 49ers-Cards reopened tonight at Arizona -3.

San Francisco has gotten 62% of early spread bets at DK, but spread money is almost dead even. However, action could be on the move once there's more clarity on Purdy's status.

UPDATE 10:30 P.M. ET SUNDAY: San Francisco (6-9 SU/5-10 ATS) isn't yet out of Week 17 in its disappointing and injury-riddled season. The Niners host Detroit on Monday night.

Arizona (7-9 SU/10-6 ATS) gave the L.A. Rams all they could handle in Week 18. The Cardinals nearly pulled off the upset, with first-and-goal at the 5-yard line in the final minute. But Kyler Murray's pass to Trey McBride deflected off McBride's helmet, and L.A.'s Ahkello Witherspoon intercepted it.

That left the Cards with a 13-9 loss, while covering as 6.5-point road pups. Arizona certainly had a shot in the NFC West, but went 1-5 SU in its last six games.

San Fran opened -1.5 vs. Arizona tonight in The SuperBook's Week 18 NFL odds. The first move was straight to pick 'em within a few minutes.

Minnesota Vikings vs. Detroit Lions Odds

Jared Goff and the Lions face a formidable Week 18 test vs. the Vikings. (Getty)
Matchup Spread Total Moneyline
Lions vs
Vikings
-2.5 (-118)
+2.5 (-102)
o56.5 (-110)
u56.5 (-110)
-148
+124
  • Opening point spread: Lions -3.5
  • Opening moneyline: Lions -150/Vikings +130
  • Opening total: Over/Under 52.5 points scored
  • Time: 8:20 p.m. ET Sunday (NBC)

UPDATE 8 P.M. ET WEDNESDAY: Detroit opened as 3-point chalk in Borgata Sports' NFL odds Week 18 market. There's been no movement so far.

"We are writing tickets on both sides at that number," Borgata sportsbook director Tom Gable said. "This one is obviously the most meaningful game of Week 18, with the winner securing the No. 1 seed in the NFC and the loser falling to the No. 5."

Gable noted the total nudged from an already-huge 56.5 to 57, with early money coming in on the Over.

UPDATE 11:15 P.M. ET MONDAY: Detroit (14-2 SU/11-4-1 ATS) tuned up nicely for a Week 18 matchup to determine the NFC's No. 1 seed. The Lions trailed San Francisco 21-13 at halftime, but went on a 27-7 scoring binge en route to a 40-34 victory.

Jared Goff & Co. covered as 4-point favorites.

DraftKings opened Vikings-Lions at Detroit -2.5 (-115) Sunday night. After the Lions' win over San Fran, the spread bumped to Lions -3 (-102). Early spread tickets are running 2/1 and early spread money 4/1 on Detroit.

The total opened at 51 and is already up to 54.5. Ticket count is 6/1 on the Over, and practically all the early money is on the Over.

UPDATE 10:30 P.M. ET SUNDAY: Minnesota (14-2 SU/11-5-1 ATS) remains in contention for the No. 1 seed in the NFC. In Week 17, the Vikings built a 27-10 lead, then held off Green Bay to win 27-25 as 1-point home favorites.

Detroit (13-2 SU/10-4-1 ATS) still has Week 17 work to do. The Lions, aiming for the NFC's No. 1 seed and a bye, travel to San Francisco for the Monday night game.

Use our best NFL betting sites for the huge Vikings vs Lions matchup!

Vikings-Lions opened at Detroit -3.5 in The SuperBook's NFL Week 18 odds market. The spread went to Lions -3 flat in a hurry, then to -3 (even). The total nudged from 52.5 to 52.

"We assumed this game will be on Sunday Night Football," SuperBook vice president John Murray said. "Minnesota continues to impress. We saw a lot of sharp money on Green Bay this week, and the Vikings handled the Packers with relative ease.

"We’re now at Vikings +3 (-120), after seeing some money show up on the 'dog."

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